{"product_id":"recombinant-human-transmembrane-emp24-like-trafficking-protein-10-bhp11004079","title":"Recombinant Human Transmembrane Emp24-Like Trafficking Protein 10","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Transmembrane Emp24-Like Trafficking Protein 10\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eTMED10, which has a GOLD domain, belongs to the EMP24\/GP25L\/p24 family. TMED10, a type I membrane protein is restricted to the plasma membrane and golgi cisternae and takes part in vesicular protein transferring. Additionally, TMED10 is a fragment of the heteromeric secretase complex and controls the complex's gamma- secretase activity without influencing its epsilon-secretase activity. Alterations in TMED10 are linked to early-onset familial Alzheimer's disease. TMED10 has a pseudogene on chromosome 8.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038136164717,"sku":"pro-1636-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038449918317,"sku":"pro-1636-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"0.1 mg","offer_id":53038449951085,"sku":"pro-1636-01MG","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-tmed10-human-PRO-1636.png?v=1782158304","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-transmembrane-emp24-like-trafficking-protein-10-bhp11004079","provider":"BioHippo","version":"1.0","type":"link"}