{"product_id":"recombinant-human-tyr-3-trp-5-monooxygenase-activation-protein-epsilon-bhp11000852","title":"Recombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, Epsilon","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, Epsilon\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eThe 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. The 14-3-3 epsilon, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038064009581,"sku":"pka-253-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038311080301,"sku":"pka-253-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038311113069,"sku":"pka-253-1MG","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ywhae-human-PKA-253.png?v=1782158158","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-tyr-3-trp-5-monooxygenase-activation-protein-epsilon-bhp11000852","provider":"BioHippo","version":"1.0","type":"link"}