{"product_id":"recombinant-human-tyr-3-trp-5-monooxygenase-activation-protein-sigma-bhp11000883","title":"Recombinant Human Tyr-3\/trp-5 Monooxygenase Activation Protein, Sigma","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Tyr-3\/trp-5 Monooxygenase Activation Protein, Sigma\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eStratifin is part of the 14-3-3 family. The 14-3-3 family of proteins plays an important regulatory function in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are 7 isoforms, beta, gamma, epsilon, sigma, zeta, tau and eta that have been identified in mammals. Stratifin is an epithelial cell marker that functions as a tumor suppressor whose expression can be down regulated via methylation. Failure of Stratifin expression results in a defective G2\/M phase checkpoint and results in epithelial and non-epithelial tumorigenesis.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038064697709,"sku":"pka-357-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038312522093,"sku":"pka-357-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038312554861,"sku":"pka-357-1MG","price":2250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-stratifin-human-PKA-357.png?v=1782158159","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-tyr-3-trp-5-monooxygenase-activation-protein-sigma-bhp11000883","provider":"BioHippo","version":"1.0","type":"link"}