{"product_id":"recombinant-human-zw10-interacting-kinetochore-protein-bhp11004223","title":"Recombinant Human ZW10 Interacting Kinetochore Protein","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human ZW10 Interacting Kinetochore Protein\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eZW10 Interacting Kinetochore Protein (ZWINT) is involved in kinetochore function. ZWINT is part of the MIS12 complex, which is essential for kinetochore formation and spindle checkpoint activity. ZWINT is localized to the cytoplasm during interphase and to kinetochores from late prophase to anaphase. ZWINT interacts with ZW10 (Zeste White 10) and regulates the association between ZW10 and kinetochores. ZWINT gene defects are linked with the pathogenesis of Roberts’s syndrome, an autosomal recessive disorder characterized by growth retardation due to premature chromosome separation.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038140555629,"sku":"pro-1944-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038459715949,"sku":"pro-1944-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"0.1 mg","offer_id":53038459748717,"sku":"pro-1944-01MG","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-zwint-human-PRO-1944.png?v=1782158313","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-zw10-interacting-kinetochore-protein-bhp11004223","provider":"BioHippo","version":"1.0","type":"link"}