{"product_id":"recombinant-macaca-fascicularis-neural-cell-adhesion-molecule-l1-l1cam-partial-active-bhp10516977","title":"Recombinant Macaca fascicularis Neural cell adhesion molecule L1 (L1CAM), partial (Active)","description":"\u003ch2\u003eOverview\u003c\/h2\u003e \u003cp\u003eThis product is a recombinant crab-eating macaque L1CAM protein commonly used as a defined reagent for assay development, interaction studies, and cell-based functional experiments. \u003c\/p\u003e \u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e \u003cul\u003e \u003cli\u003e\n\u003cstrong\u003eExpression region:\u003c\/strong\u003e 20-1120aa — region selection can affect binding epitopes and functional interpretation.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eExpression system:\u003c\/strong\u003e Mammalian cell — expression context can influence folding and post-translational features.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eConjugate\/format:\u003c\/strong\u003e C-terminal 10xHis-tagged — useful for platform-specific capture or detection workflows.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eFormat note:\u003c\/strong\u003e Labeled as active in the product title; confirm compatibility with your assay design.\u003c\/li\u003e \u003c\/ul\u003e \u003ch2\u003eBiological background\u003c\/h2\u003e \u003cp\u003eNeural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis.\u003c\/p\u003e \u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eReceptor\/ligand pathway studies in neuronal or glial models and derived systems.\u003c\/li\u003e \u003cli\u003eComparative studies of isoforms\/domains that influence synaptic or trophic signaling.\u003c\/li\u003e \u003cli\u003eUse in binding assays to characterize interactions relevant to neural development or repair.\u003c\/li\u003e \u003c\/ul\u003e \u003ch2\u003eCommon research applications\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eUse as a reagent for consistent dosing across in vitro assays\u003c\/li\u003e \u003cli\u003eGenerate standard curves or spike-in controls in buffer or sample matrix for plate assays\u003c\/li\u003e \u003cli\u003eProfile protein–protein interactions involving L1CAM using pull-down or co-binding assays\u003c\/li\u003e \u003c\/ul\u003e \u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eConsider isoforms, processing, or post-translational modifications that may differ from endogenous protein across systems.\u003c\/li\u003e \u003cli\u003eFor tagged or labeled formats, confirm that the tag does not occlude binding sites relevant to your readout.\u003c\/li\u003e \u003cli\u003eUse appropriate negative\/positive controls and orthogonal assays when interpreting binding or activity differences.\u003c\/li\u003e \u003c\/ul\u003e \u003c!-- Sources (internal): - UniProt Knowledgebase (UniProt): https:\/\/www.uniprot.org\/ - NCBI Gene (NIH\/NCBI): https:\/\/www.ncbi.nlm.nih.gov\/gene\/ - NCBI Protein (NIH\/NCBI): https:\/\/www.ncbi.nlm.nih.gov\/protein\/ - Reactome Pathway Database: https:\/\/reactome.org\/ - KEGG Pathway Database: https:\/\/www.kegg.jp\/ --\u003e","brand":"CUSABIO TECHNOLOGY LLC","offers":[{"title":"1 mg","offer_id":53059854598509,"sku":"CSB-MP6775MOV-1MG","price":2136.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53059919282541,"sku":"CSB-MP6775MOV-100UG","price":294.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53059919315309,"sku":"CSB-MP6775MOV-20UG","price":118.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/CSB-MP6775MOV-SDS.jpg?v=1772294679","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-macaca-fascicularis-neural-cell-adhesion-molecule-l1-l1cam-partial-active-bhp10516977","provider":"BioHippo","version":"1.0","type":"link"}