{"product_id":"recombinant-mouse-cytotoxic-t-lymphocyte-associated-antigen-4-bhp11000418","title":"Recombinant Mouse Cytotoxic T-Lymphocyte Associated Antigen-4","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Mouse Cytotoxic T-Lymphocyte Associated Antigen-4\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCTLA-4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with ins.-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038049722733,"sku":"cyt-950-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038283489645,"sku":"cyt-950-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038283522413,"sku":"cyt-950-1MG","price":3000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ctla4-mouse-CYT-950.png?v=1782158130","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-mouse-cytotoxic-t-lymphocyte-associated-antigen-4-bhp11000418","provider":"BioHippo","version":"1.0","type":"link"}