{"product_id":"recombinant-mouse-endostatin-c-6his-bhp15200193","title":"Recombinant Mouse Endostatin (C-6His)","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eEndostatin\u003c\/strong\u003e is a target studied in ecm \u0026amp; cell adhesion research. The sections below provide general scientific background to support interpretation-focused decision making.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGene\/target\u003c\/strong\u003e: Endostatin\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlternative names\u003c\/strong\u003e: antiangiogenic agent, COL18A1, collagen alpha-1(XVIII)chain\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAccession\u003c\/strong\u003e: P39061\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecies context\u003c\/strong\u003e: Mouse\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eSequence\/region note:\u003c\/strong\u003e Recombinant constructs are often produced as defined fragments or domains. This product corresponds to an expressed region annotated as \u003cstrong\u003eHis1591-Lys1774\u003c\/strong\u003e, which may represent a specific portion of the full-length protein used for controlled studies.\u003c\/p\u003e\u003ch2\u003eBiological role and pathway context\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eEndostatin\u003c\/strong\u003e is frequently discussed in gene-regulatory programs where transcription factors and cofactors shape cell state and stimulus responses. Regulatory effects can be highly context dependent, varying with cell type, chromatin state, and upstream signaling inputs.\u003c\/p\u003e\u003cp\u003eIn \u003cstrong\u003eECM \u0026amp; Cell Adhesion\u003c\/strong\u003e research, Endostatin is often discussed within themes such as mechanistic biology studies, pathway-level interpretation, comparative model systems. These themes can help frame interpretation of molecular measurements in relation to broader biological programs.\u003c\/p\u003e\u003cp\u003eIn many studies, transcriptional regulators are interpreted through both direct target-gene programs and indirect network effects. Changes may reflect altered expression, localization, or modification state, so integration with complementary pathway markers is commonly used to strengthen interpretation.\u003c\/p\u003e\u003cp\u003eRelated molecules may include upstream signaling nodes, cofactors, and pathway markers that reflect activation state or differentiation programs.\u003c\/p\u003e\u003ch2\u003eExpression and regulation\u003c\/h2\u003e\u003cp\u003eExpression of \u003cstrong\u003eEndostatin\u003c\/strong\u003e can be regulated at multiple levels, including transcriptional control, mRNA stability, translation, and protein turnover. Many targets also exhibit context-dependent expression across tissues or model systems and may respond dynamically to stress, growth cues, immune stimulation, or metabolic state. When comparing datasets, consider species, cell type, stimulus, and time course.\u003c\/p\u003e\u003ch2\u003eIsoforms and molecular forms\u003c\/h2\u003e\u003cp\u003eMany proteins exist as alternative isoforms or processed forms, and post-translational modifications (for example, phosphorylation, glycosylation, acetylation, or proteolytic processing) can alter localization, interactions, or activity. When interpreting results involving \u003cstrong\u003eEndostatin\u003c\/strong\u003e, consider whether studies distinguish full-length protein from specific domains or fragments, and whether modification states are relevant to the biological question.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePathway interpretation:\u003c\/strong\u003e helps connect molecular changes to network-level hypotheses in ecm \u0026amp; cell adhesion studies.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eComparative analysis:\u003c\/strong\u003e supports cross-condition or cross-model comparisons when nomenclature and context are aligned.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystems context:\u003c\/strong\u003e often interpreted alongside related pathway components to distinguish direct effects from secondary changes.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eDisease and process relevance\u003c\/h2\u003e\u003cp\u003eDepending on the target, published studies may report associations between \u003cstrong\u003eEndostatin\u003c\/strong\u003e and disease mechanisms or physiological processes. Such associations are typically context dependent and are best interpreted alongside complementary markers and functional readouts, rather than as standalone evidence.\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"10 ug","offer_id":53012030587245,"sku":"EPT193-10UG","price":219.7,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/1hlhkoede157u6613b_48e31dbf-5134-483a-81fb-01e7487d5e4c.jpg?v=1770440722","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-mouse-endostatin-c-6his-bhp15200193","provider":"BioHippo","version":"1.0","type":"link"}