{"product_id":"recombinant-mouse-glial-derived-neurotrophic-factor-bhp11002721","title":"Recombinant Mouse Glial-Derived Neurotrophic Factor","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Mouse Glial-Derived Neurotrophic Factor\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eGDNF promotes the survival and differentiation of neurons in culture, and is able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung disease. GDNF enhances survival and morphological differentiation of neurons and increases their high-affinity uptake.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038090092909,"sku":"cyt-243-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038361903469,"sku":"cyt-243-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038361936237,"sku":"cyt-243-1MG","price":4680.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-gdnf-mouse-CYT-243.png?v=1782158215","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-mouse-glial-derived-neurotrophic-factor-bhp11002721","provider":"BioHippo","version":"1.0","type":"link"}