{"product_id":"recombinant-mouse-leucine-rich-repeats-and-immunoglobulin-like-domains-1-bhp11006129","title":"Recombinant Mouse Leucine Rich Repeats And Immunoglobulin Like Domains 1","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Mouse Leucine Rich Repeats And Immunoglobulin Like Domains 1\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eLeucine Rich Repeats And Immunoglobulin Like Domains 1 or LRIG1 is a protein, acting as is a pan-negative regulator of EGFR signal transduction. When studied along with ErbB proteins and Met kinase, LRIG1 was found to have regulation activities such as ubiquitination and lysosomal degradation increment of the receptors. Therefore, LRIG1 acts as a suppressor for tumors via cell proliferation control via negative regulation of tyrosine kinase receptors that belongs to the EGF protein family. LRIG1 expression is downregulated in cancer, and acts a prognostic tool for cancer development.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038184366445,"sku":"pro-2656-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038551138669,"sku":"pro-2656-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038551171437,"sku":"pro-2656-1MG","price":4500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-lrig1-mouse-PRO-2656.png?v=1782158395","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-mouse-leucine-rich-repeats-and-immunoglobulin-like-domains-1-bhp11006129","provider":"BioHippo","version":"1.0","type":"link"}