{"product_id":"recombinant-ovine-growth-hormone-binding-protein-bhp11002330","title":"Recombinant Ovine Growth Hormone Binding Protein","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Ovine Growth Hormone Binding Protein\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eGHBP is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038077870445,"sku":"cyt-470-5UG","price":50.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038337884525,"sku":"cyt-470-20UG","price":130.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038337917293,"sku":"cyt-470-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ghbp-ovine-CYT-470.png?v=1782158187","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-ovine-growth-hormone-binding-protein-bhp11002330","provider":"BioHippo","version":"1.0","type":"link"}