{"product_id":"recombinant-phospholipase-a2-p00630-bee-venom-protein-bhp11002816","title":"Recombinant Phospholipase A2 P00630 Bee Venom Protein","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Phospholipase A2 P00630 Bee Venom Protein\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eBee venom phospholipase A2 (PLA) is the main allergen in the bee sting allergy. Bee venom phospholipase A2 (BV-PLA2) is a hydrolytic enzyme which specifically cleaves the sn-2 acyl bond of phospholipids at the lipid\/water interface. BV-PLA2 is a 14–16-kDa glycoprotein, consisting of 134 amino acids and displaying a single carbohydrate side chain at the residue Asn13. It is also held to be responsible for some systemic anaphylactic reactions in bee venom sensitized individuals. BV-PLA2 presents 3 peptide and a glycopeptide T cell epitopes, which are recognized by both allergic and non-allergic bee venom sensitized subjects. PLA is able to elicit both IgE mediated allergy and normal immunity to bee sting which usually is associated with high affinity IgG4 anti-PLA antibodies.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"100 ug","offer_id":53038093042029,"sku":"alr-001-100UG","price":165.0,"currency_code":"USD","in_stock":true},{"title":"0.5 mg","offer_id":53038368981357,"sku":"alr-001-05MG","price":660.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038369014125,"sku":"alr-001-1MG","price":1350.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-phospholipase-a2-ALR-001.png?v=1782158220","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-phospholipase-a2-p00630-bee-venom-protein-bhp11002816","provider":"BioHippo","version":"1.0","type":"link"}