{"product_id":"recombinant-rat-amphoterin-induced-protein-3-amigo3-bhp10505760","title":"Recombinant Rat Amphoterin-induced protein 3 (Amigo3)","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eThis Recombinant Protein provides recombinant \u003cstrong\u003eAmigo3\u003c\/strong\u003e from Rattus norvegicus (Rat), produced in Mammalian cell (region 20-383aa). It is commonly used as a defined reagent for assay development, binding studies, and mechanistic research (RUO).\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRegion:\u003c\/strong\u003e 20-383aa (domain boundaries can affect binding\/activity readouts).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpression host:\u003c\/strong\u003e Mammalian cell (may differ from native PTMs\/processing).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTag(s):\u003c\/strong\u003e His, Myc (supports purification\/detection; consider tag effects in controls).\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cp\u003eAlso reported as AMIGO-3 Alivin-3. May mediate heterophilic cell-cell interaction. May contribute to signal transduction through its intracellular domain.\u003c\/p\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eQuantitative mapping of ligand\/receptor signaling to downstream phospho- and transcriptional programs.\u003c\/li\u003e\n\u003cli\u003eUse of recombinant standards to improve assay calibration and cross-study comparability.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eMay mediate heterophilic cell-cell interaction. May contribute to signal transduction through its intracellular domain.\u003c\/p\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eStandard curve or spike-in reference for quantitative assays involving Amigo3\u003c\/li\u003e\n\u003cli\u003eBinding and specificity benchmarking for detection reagents (conceptual)\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eRecombinant constructs may not capture all native isoforms or PTMs.\u003c\/li\u003e\n\u003cli\u003eConsider tag- or host-related effects when interpreting binding or activity.\u003c\/li\u003e\n\u003cli\u003eUse appropriate blanks and matrix\/control concepts to separate signal from background.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c!-- Sources (internal): - UniProtKB Q80ZD5 — UniProt — https:\/\/www.uniprot.org\/uniprotkb\/Q80ZD5 - NCBI Gene search: Amigo3 — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=Amigo3 - Ensembl search: Amigo3 — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=Amigo3 - Reactome Pathway Browser — Reactome — https:\/\/reactome.org\/ - NCBI Bookshelf — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/books\/ --\u003e","brand":"CUSABIO TECHNOLOGY LLC","offers":[{"title":"1 mg","offer_id":53053368303981,"sku":"CSB-MP802260RA-1MG","price":3520.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53053459300717,"sku":"CSB-MP802260RA-100UG","price":470.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53053459333485,"sku":"CSB-MP802260RA-20UG","price":290.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/CSB-MP802260RA-SDS.jpg?v=1772177509","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-rat-amphoterin-induced-protein-3-amigo3-bhp10505760","provider":"BioHippo","version":"1.0","type":"link"}