{"product_id":"recombinant-rat-interleukin-4-bhp11000600","title":"Recombinant Rat Interleukin-4","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Rat Interleukin-4\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eIL4 is a pleiotropic cytokine produced by activated T cells. IL4 is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. IL4, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e\n\u003ch3\u003eQuality notes\u003c\/h3\u003e\n\u003cp\u003eProtein quantitation was carried out by two independent methods:\u003cbr\u003e1. UV spectroscopy at 280 nm using the absorbency value of 0.2 as the extinction coefficient for a 0.1% (1mg\/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics).\u003cbr\u003e2. Analysis by RP-HPLC, using a standard solution of IL-4 as a Reference Standard.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038056374637,"sku":"cyt-385-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038294729069,"sku":"cyt-385-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038294761837,"sku":"cyt-385-1MG","price":2900.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-il-4-rat-CYT-385.png?v=1782158141","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-rat-interleukin-4-bhp11000600","provider":"BioHippo","version":"1.0","type":"link"}