{"product_id":"recombinant-vaccinia-virus-14-kda-fusion-protein-a27l-bhp10507005","title":"Recombinant Vaccinia virus 14 kDa fusion protein (A27L)","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eThis Recombinant Protein provides recombinant \u003cstrong\u003eA27L\u003c\/strong\u003e from Vaccinia virus (strain Copenhagen) (VACV), produced in Baculovirus (region 1-110aa). It is commonly used as a defined reagent for assay development, binding studies, and mechanistic research (RUO).\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRegion:\u003c\/strong\u003e 1-110aa (domain boundaries can affect binding\/activity readouts).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpression host:\u003c\/strong\u003e Baculovirus (may differ from native PTMs\/processing).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTag(s):\u003c\/strong\u003e His, Myc (supports purification\/detection; consider tag effects in controls).\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cp\u003eAlso reported as A27L14 kDa fusion protein. Structural protein involved in the envelopment of mature virion to form the wrapped virion. The wrapping consists of the addition of Golgi membranes to the mature virion. Participates in mature virion movement within the infected cell. May play an indirect role in MV-cell fusion.\u003c\/p\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\u003cli\u003eUse of recombinant standards to improve assay calibration and cross-study comparability.\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003eStructural protein involved in the envelopment of mature virion to form the wrapped virion. The wrapping consists of the addition of Golgi membranes to the mature virion. Participates in mature virion movement within the infected cell. May play an indirect role in MV-cell fusion.\u003c\/p\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eStandard curve or spike-in reference for quantitative assays involving A27L\u003c\/li\u003e\n\u003cli\u003eBinding and specificity benchmarking for detection reagents (conceptual)\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eRecombinant constructs may not capture all native isoforms or PTMs.\u003c\/li\u003e\n\u003cli\u003eConsider tag- or host-related effects when interpreting binding or activity.\u003c\/li\u003e\n\u003cli\u003eUse appropriate blanks and matrix\/control concepts to separate signal from background.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c!-- Sources (internal): - UniProtKB P20535 — UniProt — https:\/\/www.uniprot.org\/uniprotkb\/P20535 - NCBI Gene search: A27L — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=A27L - Ensembl search: A27L — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=A27L - Reactome Pathway Browser — Reactome — https:\/\/reactome.org\/ - NCBI Bookshelf — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/books\/ --\u003e","brand":"CUSABIO TECHNOLOGY LLC","offers":[{"title":"1 mg","offer_id":53053399138669,"sku":"CSB-BP324948VAA-1MG","price":3278.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53053520544109,"sku":"CSB-BP324948VAA-100UG","price":1478.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53053520576877,"sku":"CSB-BP324948VAA-20UG","price":528.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/CSB-BP324948VAA-1.jpg?v=1772177626","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-vaccinia-virus-14-kda-fusion-protein-a27l-bhp10507005","provider":"BioHippo","version":"1.0","type":"link"}