{"product_id":"ribulose-1-5-bisphosphate-carboxylase-oxygenase-bhp10506091","title":"Ribulose-1,5-bisphosphate carboxylase oxygenase","description":"\u003ch2\u003eOverview\u003c\/h2\u003e \u003cp\u003eNative spinach RuBisCO (ribulose-1,5-bisphosphate carboxylase\/oxygenase) is purified from spinach leaf and supplied as a research reagent. It is commonly used as a reference material in biochemical and analytical workflows, and to support interpretation when naturally occurring proteoforms (for example, glycosylation or other post‑translational modifications) may matter.\u003c\/p\u003e \u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e \u003cul\u003e \u003cli\u003e\n\u003cstrong\u003eNative-source preparation:\u003c\/strong\u003e Purified from a biological source, which can be useful when studying naturally occurring proteoforms and complex formation.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eMolecular form:\u003c\/strong\u003e Full length protein.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eClassification:\u003c\/strong\u003e Photosynthetic Protein\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;95%(SDS-PAGE) (as reported).\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Liquid\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eCommon names \/ aliases:\u003c\/strong\u003e RuBisCO\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThese elements help determine how the reagent behaves in binding, stability, or quantitative measurements, and how closely it reflects biology in the chosen model system.\u003c\/p\u003e \u003ch2\u003eBiological background\u003c\/h2\u003e \u003cp\u003eRibulose-1,5-bisphosphate carboxylase\/oxygenase (RuBisCO) catalyzes the first major step of carbon fixation in the Calvin cycle by converting CO₂ into organic carbon. It also catalyzes a competing oxygenation reaction, linking RuBisCO function to photorespiration and overall photosynthetic efficiency.\u003c\/p\u003e\u003cp\u003eRibulose-1,5-bisphosphate carboxylase oxygenase, most commonly known by the shorter name RuBisCO,is an enzyme involved in the Calvin cycle that catalyzes the first major step of carbon fixation, a process by which the atoms of atmospheric carbon dioxide are made available to organisms in the form of energy-rich molecules such as glucose. RuBisCO catalyzes either the carboxylation or the oxygenation of ribulose-1,5-bisphosphate (also known as RuBP) with carbon dioxide or oxygen.\u003c\/p\u003e \u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eEngineering and directed-evolution efforts aimed at improving RuBisCO kinetics or specificity to enhance crop productivity.\u003c\/li\u003e \u003cli\u003eSystems biology of photosynthesis and photorespiration under changing CO₂ and temperature conditions.\u003c\/li\u003e \u003cli\u003eUse of RuBisCO abundance as a normalization anchor in some plant proteomics contexts (RUO).\u003c\/li\u003e \u003c\/ul\u003e \u003ch2\u003eCommon research applications\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eEnzyme and pathway studies focused on carbon fixation and photosynthetic regulation.\u003c\/li\u003e \u003cli\u003eBenchmark protein for plant protein extraction and analytical workflows.\u003c\/li\u003e \u003cli\u003eComparative research on RuBisCO isoforms and organism-specific adaptations.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eUse changes in abundance, binding, or activity readouts as context-dependent signals. In many systems, differences may reflect regulation, compartment shifts, complex formation, or sample-matrix effects rather than a single direct mechanism.\u003c\/p\u003e \u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eRuBisCO activity depends on cofactors and interacting proteins (e.g., chaperones\/activase); isolated protein may not capture full in vivo regulation.\u003c\/li\u003e \u003cli\u003ePreparations from different species can differ in subunit composition and kinetics; align source with your experimental question.\u003c\/li\u003e \u003cli\u003eCarbon-fixation readouts are pathway-level; interpret enzyme-level changes in the context of broader photosynthetic regulation.\u003c\/li\u003e \u003c\/ul\u003e \u003c!-- Sources (internal): - UniProt: https:\/\/www.uniprot.org\/uniprotkb?query=RuBisCO ribulose-1,5-bisphosphate carboxylase oxygenase - NCBI Gene: https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=RuBisCO ribulose-1,5-bisphosphate carboxylase oxygenase - PubMed: https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=RuBisCO ribulose-1,5-bisphosphate carboxylase oxygenase%20review --\u003e","brand":"CUSABIO TECHNOLOGY LLC","offers":[{"title":"10 mg","offer_id":53052973875565,"sku":"CSB-NP001701Pl-10MG","price":500.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53052973908333,"sku":"CSB-NP001701Pl-1MG","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/CSB-NP001701Pl-SDS.jpg?v=1772166487","url":"https:\/\/www.ebiohippo.com\/products\/ribulose-1-5-bisphosphate-carboxylase-oxygenase-bhp10506091","provider":"BioHippo","version":"1.0","type":"link"}