{"product_id":"rm-1-cell-bhc11101064","title":"RM-1 cell","description":"The RM-1 cell line is a fibroblast-like model derived from the embryonic prostate tissue of C57BL\/6 mouse embryos. These cells were isolated from 17-day-old urogenital sinus cells and infected with the Zipras\/myc9 retrovirus, containing the oncogenes v-Ha-Ras and v-Myc. RM-1 cells exhibit high tumorigenic potential, forming poorly differentiated mouse prostate carcinomas with high frequency.\nRM-1 cells are positive for cytokeratin 18 mRNA and immunoreactive to cytokeratin-specific antiserum, indicating epithelial origin. They demonstrate significant mitogenic response to testosterone, with approximately a two-fold increase in cell number under serum-free conditions. This cell line maintains stable androgen receptor numbers and binding kinetics across multiple passages, making it a valuable model for studying androgen sensitivity and prostate cancer progression.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101064\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950222995821,"sku":"305168","price":550.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/rm-1-_282_29_1920x1920_f0bd984d-9ff4-4fac-a359-a8d8b2d6ac46.jpg?v=1769069210","url":"https:\/\/www.ebiohippo.com\/products\/rm-1-cell-bhc11101064","provider":"BioHippo","version":"1.0","type":"link"}