{"product_id":"rrn3-antibody-tif-ia-rna-polymerase-i-specific-transcription-initiation-factor-rrn3-bha17135163","title":"RRN3 Antibody \/ TIF-IA \/ RNA polymerase I-specific transcription initiation factor RRN3","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eRRN3 Antibody \/ TIF-IA \/ RNA polymerase I-specific transcription initiation factor RRN3 is an antibody targeting \u003cstrong\u003eRRN3\u003c\/strong\u003e. Host: \u003cstrong\u003eRabbit\u003c\/strong\u003e. Polyclonal. Format: Lyophilized. Applications: WB, FACS, ELISA.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e RRN3.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunogen:\u003c\/strong\u003e E.coli-derived human RRN3 recombinant protein (Position: D184-L651) was used as the immunogen for the RRN3 antibody..\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecies reactivity:\u003c\/strong\u003e Human.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConjugate:\u003c\/strong\u003e Unconjugated (no label listed).\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background (from provided description)\u003c\/h2\u003e\u003cp\u003eRRN3 antibody detects RNA polymerase I-specific transcription initiation factor RRN3, encoded by the RRN3 gene on chromosome 16p13.11. RRN3 antibody is widely used in studies of transcriptional regulation, ribosome biogenesis, and cell growth. RRN3 is a transcription factor that links RNA polymerase I to the transcription machinery at ribosomal DNA (rDNA) promoters, initiating rRNA synthesis.\u003c\/p\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\u003cli\u003e\n\u003cstrong\u003eWB:\u003c\/strong\u003e relative abundance and band pattern assessment using appropriate controls.\u003c\/li\u003e\u003c\/ul\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eAccount for isoforms, paralogs, and post-translational modifications when interpreting signal.\u003c\/li\u003e\n\u003cli\u003eSupport specificity with biological controls (e.g., KO\/KD where available) and technical controls (e.g., secondary-only\/isotype).\u003c\/li\u003e\n\u003c\/ul\u003e\u003c!-- Sources (internal): - UniProt Knowledgebase (UniProt) – https:\/\/www.uniprot.org\/ - NCBI Gene (NIH\/NLM) – https:\/\/www.ncbi.nlm.nih.gov\/gene\/ - ZFIN – https:\/\/zfin.org\/ - Ensembl – https:\/\/www.ensembl.org\/ - Nature Methods (2015): A proposal for validation of antibodies – https:\/\/www.nature.com\/articles\/nmeth.3230 --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"Adding 0.2 ml of distilled water will yield a concentration of 500 ug\/ml \/ 100 ug","offer_id":53046720823661,"sku":"FY12260","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_81bd7bba-d8fc-42dd-8aad-14d380fd3b8d.jpg?v=1782236976","url":"https:\/\/www.ebiohippo.com\/products\/rrn3-antibody-tif-ia-rna-polymerase-i-specific-transcription-initiation-factor-rrn3-bha17135163","provider":"BioHippo","version":"1.0","type":"link"}