{"product_id":"sglt1-antibody-sodium-glucose-cotransporter-1-bha17128449","title":"SGLT1 Antibody \/ Sodium\/glucose cotransporter 1","description":"\u003ch2\u003eOverview\u003c\/h2\u003e \u003cp\u003eSGLT1 Antibody \/ Sodium\/glucose cotransporter 1 is an antibody targeting \u003cstrong\u003eSGLT1\u003c\/strong\u003e, raised in \u003cstrong\u003eGoat\u003c\/strong\u003e for protein detection and localization studies where these specifications are required.\u003c\/p\u003e \u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e \u003cul\u003e \u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e SGLT1.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eAntibody identity:\u003c\/strong\u003e Polyclonal (goat origin); Goat Ig.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eConjugate\/label:\u003c\/strong\u003e Unconjugated (affects detection chemistry and multiplex compatibility).\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Antigen affinity purified.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eSpecies reactivity:\u003c\/strong\u003e Human.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eListed applications:\u003c\/strong\u003e IHC-P, ELISA (peptide) (refer to on-page specifications for application-specific guidance).\u003c\/li\u003e \u003c\/ul\u003e  \u003ch2\u003eBiological background\u003c\/h2\u003e \u003cp\u003eSodium\/glucose cotransporter 1 \/ SGLT1 is primarily found in the small intestine and the kidneys, where it facilitates the transportation of glucose and sodium across cell membranes. In the intestines, SGLT1 helps in the absorption of glucose from the food we eat, ensuring that it enters the bloodstream and provides energy to our cells. In the kidneys, SGLT1 is involved in the reabsorption of glucose from the urine back into the bloodstream, preventing its wastage and ensuring that the body retains this valuable energy source. This function becomes particularly important in cases of high blood sugar levels, such as in diabetes, where the kidneys may excrete excess glucose in the urine.\u003c\/p\u003e \u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eComparative expression profiling across cell types, tissues, or perturbations (e.g., drug treatment, genetic editing, or differentiation).\u003c\/li\u003e \u003cli\u003eSubcellular localization and trafficking studies, including co-localization with pathway markers in microscopy-based assays.\u003c\/li\u003e \u003cli\u003eIntegration of protein-level measurements with transcriptomics or proteomics to relate abundance to regulation and phenotype.\u003c\/li\u003e \u003c\/ul\u003e \u003ch2\u003eCommon research applications\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eImmunohistochemistry: researchers commonly compare relative signal levels across conditions and use appropriate negative\/positive controls for interpretation.\u003c\/li\u003e \u003cli\u003eELISA: researchers commonly compare relative signal levels across conditions and use appropriate negative\/positive controls for interpretation.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eInterpretation should account for antibody-dependent factors such as epitope accessibility, isoforms, and sample preparation differences across workflows.\u003c\/p\u003e \u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e \u003cul\u003e \u003cli\u003e\n\u003cstrong\u003eIsoforms and PTMs:\u003c\/strong\u003e many targets have multiple isoforms and post-translational modifications that can shift apparent signal or localization; interpret bands\/signals accordingly.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eEpitope context:\u003c\/strong\u003e binding can depend on protein conformation and sample processing; region information in the title\/immunogen can help anticipate what may be detected.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eSpecies differences:\u003c\/strong\u003e predicted or validated reactivity may vary by ortholog sequence and sample context; confirm in your model system.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eControl concepts:\u003c\/strong\u003e include negative controls (no-primary\/isotype), and where possible genetic controls (KO\/KD) or independent antibodies to strengthen conclusions.\u003c\/li\u003e \u003c\/ul\u003e \u003c!-- Sources (internal): - UniProtKB entry P13866 — UniProt — https:\/\/www.uniprot.org\/uniprotkb\/P13866 - Gene search: SGLT1 — NCBI Gene — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=SGLT1 - Ensembl search: SGLT1 — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=SGLT1 - PubMed search: SGLT1 antibody — PubMed — https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=SGLT1+antibody - Reactome search: SGLT1 — Reactome — https:\/\/reactome.org\/content\/query?q=SGLT1 --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.5 mg\/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide \/ 100 ug","offer_id":53046420373869,"sku":"R36501-100UG","price":475.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_ee6aff11-8da2-414c-a598-c5944740644a.jpg?v=1772000541","url":"https:\/\/www.ebiohippo.com\/products\/sglt1-antibody-sodium-glucose-cotransporter-1-bha17128449","provider":"BioHippo","version":"1.0","type":"link"}