{"product_id":"slc29a1-antibody-solute-carrier-family-29-member-1-ent1-bha17128127","title":"SLC29A1 Antibody \/ Solute carrier family 29 member 1 \/ ENT1","description":"\u003ch2\u003eOverview\u003c\/h2\u003e \u003cp\u003eSLC29A1 Antibody \/ Solute carrier family 29 member 1 \/ ENT1 is an antibody targeting \u003cstrong\u003eSLC29A1\u003c\/strong\u003e, raised in \u003cstrong\u003eRabbit\u003c\/strong\u003e for protein detection and localization studies where these specifications are required.\u003c\/p\u003e \u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e \u003cul\u003e \u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e SLC29A1.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eAntibody identity:\u003c\/strong\u003e Polyclonal (rabbit origin); Rabbit Ig.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eConjugate\/label:\u003c\/strong\u003e Unconjugated (affects detection chemistry and multiplex compatibility).\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Purified.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eSpecies reactivity:\u003c\/strong\u003e Human, Mouse.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eListed applications:\u003c\/strong\u003e WB (refer to on-page specifications for application-specific guidance).\u003c\/li\u003e \u003c\/ul\u003e  \u003ch2\u003eBiological background\u003c\/h2\u003e \u003cp\u003eSLC29A1 (Solute carrier family 29 member 1), also known as the Equilibrative nucleoside transporter 1 (ENT1), is a protein that plays a role in the transport of nucleosides across cell membranes. Nucleosides are essential components of DNA and RNA, and their transport into cells is crucial for various cellular processes, including DNA replication and protein synthesis. Recent research has also suggested that SLC29A1 protein may play a role in regulating the immune response and inflammation. Studies have shown that altered expression of SLC29A1 protein can lead to dysregulation of immune cells, contributing to inflammatory disorders and autoimmune diseases. Additionally, SLC29A1 protein has been implicated in cancer progression. Studies have shown that increased expression of SLC29A1 protein is associated with enhanced cell proliferation and survival in various cancer types. This suggests that targeting SLC29A1 protein could be a promising therapeutic strategy for cancer treatment.\u003c\/p\u003e \u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eComparative expression profiling across cell types, tissues, or perturbations (e.g., drug treatment, genetic editing, or differentiation).\u003c\/li\u003e \u003cli\u003eSubcellular localization and trafficking studies, including co-localization with pathway markers in microscopy-based assays.\u003c\/li\u003e \u003cli\u003eIntegration of protein-level measurements with transcriptomics or proteomics to relate abundance to regulation and phenotype.\u003c\/li\u003e \u003c\/ul\u003e \u003ch2\u003eCommon research applications\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eWestern blotting: researchers commonly compare relative signal levels across conditions and use appropriate negative\/positive controls for interpretation.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eInterpretation should account for antibody-dependent factors such as epitope accessibility, isoforms, and sample preparation differences across workflows.\u003c\/p\u003e \u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e \u003cul\u003e \u003cli\u003e\n\u003cstrong\u003eIsoforms and PTMs:\u003c\/strong\u003e many targets have multiple isoforms and post-translational modifications that can shift apparent signal or localization; interpret bands\/signals accordingly.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eEpitope context:\u003c\/strong\u003e binding can depend on protein conformation and sample processing; region information in the title\/immunogen can help anticipate what may be detected.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eSpecies differences:\u003c\/strong\u003e predicted or validated reactivity may vary by ortholog sequence and sample context; confirm in your model system.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eControl concepts:\u003c\/strong\u003e include negative controls (no-primary\/isotype), and where possible genetic controls (KO\/KD) or independent antibodies to strengthen conclusions.\u003c\/li\u003e \u003c\/ul\u003e \u003c!-- Sources (internal): - UniProtKB entry Q99808 — UniProt — https:\/\/www.uniprot.org\/uniprotkb\/Q99808 - Gene search: SLC29A1 — NCBI Gene — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=SLC29A1 - Ensembl search: SLC29A1 — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=SLC29A1 - PubMed search: SLC29A1 antibody — PubMed — https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=SLC29A1+antibody - Reactome search: SLC29A1 — Reactome — https:\/\/reactome.org\/content\/query?q=SLC29A1 --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"In 1X PBS, pH 7.4, with 0.09% sodium azide \/ 0.05 ml","offer_id":53046408020333,"sku":"F55064-0.05ML","price":205.0,"currency_code":"USD","in_stock":true},{"title":"In 1X PBS, pH 7.4, with 0.09% sodium azide \/ 0.2 ml","offer_id":53046466838893,"sku":"F55064-0.2ML","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_237fcf9e-26b0-487a-8231-ce831d74b19e.jpg?v=1772000490","url":"https:\/\/www.ebiohippo.com\/products\/slc29a1-antibody-solute-carrier-family-29-member-1-ent1-bha17128127","provider":"BioHippo","version":"1.0","type":"link"}