{"product_id":"slc9a3r2-antibody-fitc-conjugated-bha10524422","title":"SLC9A3R2 Antibody, FITC conjugated","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eThis is a polyclonal anti-SLC9A3R2 antibody raised in Rabbit, conjugated with FITC. It is designed to detect SLC9A3R2 protein in Human and supports researchers working in signal transduction contexts where consistent antibody performance is required.\u003c\/p\u003e\n\n\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Recombinant Human Na(+)\/H(+) exchange regulatory cofactor NHE-RF2 protein (106-313AA) — the immunizing antigen determines the epitope region; confirm epitope compatibility with sample preparation and expected post-translational modifications.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHost species (Rabbit):\u003c\/strong\u003e Requires anti-rabbit-IgG secondary reagents. Use matched secondaries to avoid no-signal or cross-reactivity issues.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePolyclonal format:\u003c\/strong\u003e Recognizes multiple epitopes, providing robust signal across varied preparations and species variants. Inherent lot-to-lot variability requires appropriate controls.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIsotype (IgG):\u003c\/strong\u003e Compatible with standard Protein A\/G purification and widely supported by secondary reagents. Include an isotype-matched control at equivalent concentration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurification (Protein G purification):\u003c\/strong\u003e Enriches for specific immunoglobulin classes, reducing non-specific populations and improving signal-to-noise.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFITC conjugate:\u003c\/strong\u003e Direct fluorescence detection (Ex ~490\/Em ~525 nm). FITC is photolabile; protect samples and use antifade reagents for slides.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eBiological background\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSLC9A3R2\u003c\/strong\u003e (also referred to as E3KARP, HGNC:11076, Isoform 3 regulator 2, Isoform 3 regulatory factor 2, MGC104639, Na(+)\/H(+) exchange regulatory cofactor NHE RF2, Na(+)\/H(+) exchange regulatory cofactor NHE-RF2, NHE3 kinase A regulatory protein, NHE3 kinase A regulatory protein E3KARP, NHE3 regulatory factor 2, NHE3RF2, NHERF 2, NHERF-2, NHERF2, NHRF2_HUMAN, OCTS2, SIP 1, SIP-1, SIP1, Slc9a3r2, Sodium hydrogen exchanger regulatory factor 2, Sodium-hydrogen exchanger regulatory factor 2, Sodium\/hydrogen exchanger, Sodium\/hydrogen exchanger regulatory factor 2, Solute carrier family 9 (sodium\/hydrogen exchanger), Solute carrier family 9 (sodium\/hydrogen exchanger) isoform 3 regulator 2, Solute carrier family 9 (sodium\/hydrogen exchanger) isoform 3 regulatory factor 2, Solute carrier family 9 (sodium\/hydrogen exchanger) member 3 regulator 2, Solute carrier family 9 isoform 3 regulator 2, Solute carrier family 9 isoform A3 regulatory factor 2, SRY interacting protein 1, SRY-interacting protein 1, TKA 1, TKA-1, TKA1, Tyrosine kinase activator protein 1) is a protein target studied in Human systems. Expression levels, subcellular localization, and post-translational modifications vary across cell types, tissues, and disease states — factors that influence antibody-based detection and experimental design. Consult UniProt, NCBI Gene, and primary literature for current annotation of SLC9A3R2 biology, including known isoforms, interactors, and disease-relevant expression patterns in signal transduction.\u003c\/p\u003e\n\n\u003ch2\u003eCommon research applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eRefer to product documentation for confirmed application data and recommended conditions.\u003c\/li\u003e\n\n\u003c\/ul\u003e\n\n\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIsotype controls:\u003c\/strong\u003e Use an isotype-matched (IgG from Rabbit) control at equivalent concentration to assess non-specific background.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCross-reactivity:\u003c\/strong\u003e Polyclonal preparations may cross-react with related proteins or isoforms. Orthogonal validation (siRNA, KO lysate, recombinant protein) is recommended to confirm signal specificity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMatrix effects:\u003c\/strong\u003e Sample matrix (serum, plasma, lysate, homogenate) can affect performance. Pilot dilution linearity and spike-recovery experiments are recommended for quantitative studies.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecies reactivity:\u003c\/strong\u003e Confirmed for Human. Extrapolation to untested species requires empirical validation given potential epitope sequence divergence.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\u003cem\u003eThis product is a polyclonal antibody purified from rabbit antiserum.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003c!-- Sources (internal):\n- UniProt: https:\/\/www.uniprot.org\n- NCBI Gene: https:\/\/www.ncbi.nlm.nih.gov\/gene\n- Cusabio datasheet: https:\/\/www.cusabio.com\n- Human Protein Atlas: https:\/\/www.proteinatlas.org\n- PubMed: https:\/\/pubmed.ncbi.nlm.nih.gov\n--\u003e","brand":"CUSABIO TECHNOLOGY LLC","offers":[{"title":"50 ug","offer_id":53240387240301,"sku":"CSB-PA01759C0Rb-50UG","price":170.98,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53240494326125,"sku":"CSB-PA01759C0Rb-100UG","price":307.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Cusabio_Antibody_Placeholder_2a7bc43d-1b1d-47a4-814b-00c645cff1f7.jpg?v=1784926704","url":"https:\/\/www.ebiohippo.com\/products\/slc9a3r2-antibody-fitc-conjugated-bha10524422","provider":"BioHippo","version":"1.0","type":"link"}