{"product_id":"spautin-1-bhb11900192","title":"Spautin-1","description":"\u003cp\u003eSpautin-1 (specific and potent autophagy inhibitor 1) is a small molecule that inhibits autophagy by targeting the deubiquitinating enzymes USP10 and USP13, leading to degradation of the Beclin-1 complex. In neurodegenerative disease research, Spautin-1 is used to study the role of autophagy in neuronal survival and protein aggregation. Dysregulated autophagy is a hallmark of diseases such as Alzheimer’s, Parkinson’s, and Huntington’s, where accumulation of misfolded proteins contributes to neurotoxicity. By inhibiting autophagy, Spautin-1 helps delineate the protective versus detrimental roles of this pathway in neuronal health and degeneration. It is a valuable tool for dissecting autophagy-related mechanisms in the CNS.\u003c\/p\u003e","brand":"StressMarq Biosciences Inc.","offers":[{"title":"5 mg","offer_id":53040947003757,"sku":"SIH-404-5MG","price":94.0,"currency_code":"USD","in_stock":true},{"title":"25 mg","offer_id":53040967549293,"sku":"SIH-404-25MG","price":384.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/SIH-404_Spautin-1_Chemical_Structure.png?v=1771837649","url":"https:\/\/www.ebiohippo.com\/products\/spautin-1-bhb11900192","provider":"BioHippo","version":"1.0","type":"link"}