{"product_id":"stearoyl-coenzyme-a-lithium-salt-bhb21200063","title":"Stearoyl Coenzyme A, Lithium salt","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eStearoyl Coenzyme A, Lithium salt is a biochemical supplied by Coenza for use in enzymology and metabolic research. Available as Lyophilized powder, purity ≥ 95%, suitable for in vitro assays and pathway studies.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eAlso known as:\u003c\/em\u003e n-Octadecanoyl Coenzyme A.\u003c\/p\u003e\n\u003ch2\u003eKey Elements and Design Rationale\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormula \/ MW \/ Purity:\u003c\/strong\u003e C39H67N7O17P3S · xLi; 1034.00 g\/mol (free acid basis); ≥ 95%. The Lithium salt form provides enhanced aqueous stability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm \/ Solubility:\u003c\/strong\u003e Lyophilized powder; Soluble in water.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynonyms:\u003c\/strong\u003e n-Octadecanoyl Coenzyme A.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrigin:\u003c\/strong\u003e Biosynthetic synthesis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eBiological Background\u003c\/h2\u003e\n\u003cp\u003eStearoyl coenzyme A lithium salt plays a crucial role in metabolic studies, particularly in fatty acid metabolism, by serving as a substrate for enzymes like stearoyl-CoA desaturase, which catalyzes the conversion of stearoyl-CoA to oleoyl-CoA. Stearoyl-CoA lithium salt is integral to research on lipid synthesis, polyunsaturated fatty acid formation, and the PPAR signaling pathway, and is used to investigate enzyme kinetics in processes such as fatty acid elongation and desaturation. The lithium salt form enhances solubility and stability, making it a valuable tool in exploring lipid metabolism and understanding the biochemical pathways regulating energy storage and membrane structure (Matsuzaka et al., 2002; Ntambi \u0026amp; Miyazaki, 2004).\u003c\/p\u003e\n\u003ch2\u003eResearch Relevance and Current Trends\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAcyl-CoA metabolism increasingly linked to histone acylation marks and epigenetic regulation in cancer and metabolic disease research.\u003c\/li\u003e\n\u003cli\u003eGrowing interest in short-chain fatty acid CoA thioesters as mediators of gut microbiome–host metabolic crosstalk.\u003c\/li\u003e\n\u003cli\u003eCoA-dependent enzymes investigated as drug targets in infectious disease and neurometabolic disorder research.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eCommon Research Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eEnzyme kinetics assays — direct substrate for acyltransferases, thiolases, and dehydrogenases.\u003c\/li\u003e\n\u003cli\u003eMetabolic flux analysis — isotope-labeled variants available for stable-isotope tracing.\u003c\/li\u003e\n\u003cli\u003eIn vitro pathway reconstitution for fatty acid β-oxidation, TCA cycle, or polyketide biosynthesis.\u003c\/li\u003e\n\u003cli\u003eBiochemical characterization of CoA-binding proteins by activity assays or binding measurements.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eNotes for Experimental Interpretation\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCoA thioesters hydrolyze at neutral–alkaline pH; prepare working solutions fresh and keep on ice.\u003c\/li\u003e\n\u003cli\u003eDifferent salt forms share the same core structure — normalize concentrations using the free-acid MW when comparing across forms.\u003c\/li\u003e\n\u003cli\u003eThiol oxidation may occur upon air exposure; use under inert atmosphere or with reducing agents where appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Coenza","offers":[{"title":"10 mg","offer_id":53249727463789,"sku":"A-63-10MG","price":488.7,"currency_code":"USD","in_stock":true},{"title":"25 mg","offer_id":53249733198189,"sku":"A-63-25MG","price":846.6,"currency_code":"USD","in_stock":true},{"title":"50 mg","offer_id":53249733230957,"sku":"A-63-50MG","price":1238.7,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/53dbfa_ec2d30ec180944709545097e18622023_mv2.png?v=1776855585","url":"https:\/\/www.ebiohippo.com\/products\/stearoyl-coenzyme-a-lithium-salt-bhb21200063","provider":"BioHippo","version":"1.0","type":"link"}