{"product_id":"styrene-maleic-acid-copolymer-2-1-bht16300176","title":"Styrene-Maleic Acid Copolymer 2:1","description":"\u003cstyle\u003e.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}.bhp-desc p{margin:0 0 12px}.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}.bhp-desc .bhp-spec-table th{text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}.bhp-desc .bhp-cat-pill{display:inline-block;background:#003366;color:#fff;border-radius:20px;padding:3px 12px;font-size:13px;margin-bottom:10px}.bhp-desc ol,.bhp-desc ul{margin:0 0 12px 20px}\u003c\/style\u003e\u003cdiv class=\"bhp-desc\"\u003e\n\u003cspan class=\"bhp-cat-pill\"\u003eNanodisc Reagents\u003c\/span\u003e\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eStyrene-maleic acid (SMA) copolymers are used for function and structure studies of membrane proteins. They extract membrane proteins from cell membranes and proteoliposomes without detergent and form bilayer nanodiscs with phospholipids, in which the extracted proteins are stabilized in a lipid environment that mimics the natural bilayer. Proteins in nanodiscs can be purified and used in biochemical, biophysical and biological experiments, for example structure studies by electron microscopy.\u003c\/p\u003e\n\u003cp\u003eThis copolymer has a styrene to maleic acid molar ratio of 2:1 and forms nanodiscs of about 30 nm. The ideal pH for nanodisc formation is pH 7.0–8.0.\u003c\/p\u003e\n\u003ch2\u003eProduct Description\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003cth\u003eMolecular weight\u003c\/th\u003e\n\u003cth\u003eDissolves in\u003c\/th\u003e\n\u003cth\u003eSizes\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eFree Acid\u003c\/th\u003e\n\u003ctd\u003e10.1 kDa\u003c\/td\u003e\n\u003ctd\u003epH 8.5 buffer\u003c\/td\u003e\n\u003ctd\u003e100 mg, 500 mg, 5000 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSodium Salt\u003c\/th\u003e\n\u003ctd\u003e10.4 kDa\u003c\/td\u003e\n\u003ctd\u003eWater\u003c\/td\u003e\n\u003ctd\u003e100 mg, 500 mg, 5000 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSolution, pH 7.6\u003c\/th\u003e\n\u003ctd\u003e—\u003c\/td\u003e\n\u003ctd\u003eSupplied as 5% in 0.1 M Tris-HCl, pH 7.6\u003c\/td\u003e\n\u003ctd\u003e10 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eStyrene : maleic acid (molar ratio)\u003c\/th\u003e\n\u003ctd\u003e2:1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eTypical nanodisc size\u003c\/th\u003e\n\u003ctd\u003eAbout 30 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eIdeal pH for nanodisc formation\u003c\/th\u003e\n\u003ctd\u003epH 7.0–8.0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eCatalog #\u003c\/th\u003e\n\u003ctd\u003eSMA21-100MG, SMA21-500MG, SMA21-5000MG, SMA21S-100MG, SMA21S-500MG, SMA21S-5000MG, SMA21-10ML\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStorage\u003c\/th\u003e\n\u003ctd\u003ePlease contact us to confirm storage conditions.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eShipping\u003c\/th\u003e\n\u003ctd\u003ePowders are shipped at room temperature; the solution is shipped cold.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe ProFoldin protocol “Styrene - Maleic Acid Copolymer 2:1” is linked under Documents.\u003c\/p\u003e\n\u003ch2\u003eSafety \u0026amp; Handling\u003c\/h2\u003e\n\u003cdiv class=\"bhp-warning-box\"\u003eFor Research Use Only (RUO). Not for use in diagnostic or therapeutic procedures. Follow standard laboratory safety practices.\u003c\/div\u003e\n\u003c\/div\u003e","brand":"ProFoldin","offers":[{"title":"Free Acid \/ 100 mg","offer_id":67828368212333,"sku":"SMA21-100MG","price":259.0,"currency_code":"USD","in_stock":true},{"title":"Free Acid \/ 500 mg","offer_id":67828368572781,"sku":"SMA21-500MG","price":647.0,"currency_code":"USD","in_stock":true},{"title":"Free Acid \/ 5000 mg","offer_id":67828368605549,"sku":"SMA21-5000MG","price":3081.0,"currency_code":"USD","in_stock":true},{"title":"Sodium Salt \/ 100 mg","offer_id":67828368638317,"sku":"SMA21S-100MG","price":259.0,"currency_code":"USD","in_stock":true},{"title":"Sodium Salt \/ 500 mg","offer_id":67828368671085,"sku":"SMA21S-500MG","price":647.0,"currency_code":"USD","in_stock":true},{"title":"Sodium Salt \/ 5000 mg","offer_id":67828368703853,"sku":"SMA21S-5000MG","price":3081.0,"currency_code":"USD","in_stock":true},{"title":"Solution, pH 7.6 \/ 10 ml","offer_id":67828368736621,"sku":"SMA21-10ML","price":670.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/SMA21.jpg?v=1793129722","url":"https:\/\/www.ebiohippo.com\/products\/styrene-maleic-acid-copolymer-2-1-bht16300176","provider":"BioHippo","version":"1.0","type":"link"}