{"product_id":"taurine-bhb21300337","title":"Taurine","description":"\u003ch3\u003eProduct details\u003c\/h3\u003e \u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eChemical name:\u003c\/strong\u003e 2-aminoethanesulfonic acid.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlso known as:\u003c\/strong\u003e 2-Aminoethylsulfonic acid, Tauphon\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS number:\u003c\/strong\u003e 107-35-7\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e C2H7NO3S.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;99%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConcentration:\u003c\/strong\u003e 0.05-5 mM.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilized Powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSolubility:\u003c\/strong\u003e \u0026gt;100mM in H2O. Centrifuge all product preparations before use (10000 x g 5 min).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReconstitution:\u003c\/strong\u003e \u0026gt;100mM in H2O. Centrifuge all product preparations before use (10000 x g 5 min).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShipping:\u003c\/strong\u003e Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e Glycine receptor, Taurine transporter\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSource:\u003c\/strong\u003e Synthetic\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eActivity:\u003c\/strong\u003e Taurine is a Glycine receptor (GlyR) partial agonist (EC50=1.7 mM)1. It displaces [3H]Strychnine bound to GlyR α1 expressing 293 cells membrane fraction (Ki=170 µM)2.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlternative names:\u003c\/strong\u003e 2-Aminoethylsulfonic acid, Tauphon\u003c\/li\u003e\n\u003c\/ul\u003e \u003ch3\u003eScientific background\u003c\/h3\u003e \u003cp\u003eTaurine (2-aminoethanesulfonic acid) is a β-amino acid, one of the most abundant free amino acids found in vertebrates. Taurine can be present in many tissues including brain, myocardium, and kidney. It plays an important role in several physiological processes including cardiac contraction, antioxidation, blunting of hypertension, bile acid conjugation, maintenance of calcium homeostasis, osmoregulation, and membrane stabilization.Taurine acts as an endogenous partial agonist at the inhibitory glycine receptor (GlyR)1,2.The glycine receptor is a member of the ligand-gated ion channel (LGIC) superfamily. The receptor mediates fast inhibitory neurotransmission in the mammalian spinal cord and parts of the brain3.\u003c\/p\u003e \u003cp\u003e\u003cstrong\u003eLead time:\u003c\/strong\u003e 1-2 Business Days\u003c\/p\u003e \u003cp\u003e\u003cstrong\u003eCountry of origin:\u003c\/strong\u003e Israel\/IL\u003c\/p\u003e \u003ch3\u003eApplications key\u003c\/h3\u003e \u003cp\u003eApplication key: FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay.\u003c\/p\u003e \u003cp\u003e\u003cstrong\u003eBioassay tested:\u003c\/strong\u003e Yes\u003c\/p\u003e","brand":"Alomone Labs","offers":[{"title":"10 g \/ 1","offer_id":53249714454893,"sku":"T-130-10G-1","price":66.0,"currency_code":"USD","in_stock":true},{"title":"100 g \/ 1","offer_id":53311579029869,"sku":"T-130-100G-1","price":117.0,"currency_code":"USD","in_stock":true},{"title":"25 g \/ 1","offer_id":53311579062637,"sku":"T-130-25G-1","price":85.0,"currency_code":"USD","in_stock":true},{"title":"5 g \/ 1","offer_id":53311579095405,"sku":"T-130-5G-1","price":50.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/T-130_str-1.gif?v=1778544454","url":"https:\/\/www.ebiohippo.com\/products\/taurine-bhb21300337","provider":"BioHippo","version":"1.0","type":"link"}