{"product_id":"tfb2m-antibody-transcription-factor-b2-mitochondrial-bha17135069","title":"TFB2M Antibody \/ Transcription factor B2, mitochondrial","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eTFB2M Antibody \/ Transcription factor B2, mitochondrial is an antibody targeting \u003cstrong\u003eTFB2M\u003c\/strong\u003e. Host: \u003cstrong\u003eRabbit\u003c\/strong\u003e. Polyclonal. Format: Lyophilized. Applications: WB, FACS, ELISA.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e TFB2M.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunogen:\u003c\/strong\u003e E.coli-derived human TFB2M recombinant protein (Position: R10-K386) was used as the immunogen for the TFB2M antibody..\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecies reactivity:\u003c\/strong\u003e Human.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConjugate:\u003c\/strong\u003e Unconjugated (no label listed).\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background (from provided description)\u003c\/h2\u003e\u003cp\u003eTFB2M antibody detects Transcription factor B2, mitochondrial, encoded by the TFB2M gene on chromosome 1q44. TFB2M antibody is commonly used in research on mitochondrial transcription and energy metabolism. TFB2M functions as a key initiation factor for mitochondrial RNA polymerase (POLRMT), helping to promote promoter melting and start site recognition during transcription initiation.\u003c\/p\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\u003cli\u003e\n\u003cstrong\u003eWB:\u003c\/strong\u003e relative abundance and band pattern assessment using appropriate controls.\u003c\/li\u003e\u003c\/ul\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eAccount for isoforms, paralogs, and post-translational modifications when interpreting signal.\u003c\/li\u003e\n\u003cli\u003eSupport specificity with biological controls (e.g., KO\/KD where available) and technical controls (e.g., secondary-only\/isotype).\u003c\/li\u003e\n\u003c\/ul\u003e\u003c!-- Sources (internal): - UniProt Knowledgebase (UniProt) – https:\/\/www.uniprot.org\/ - NCBI Gene (NIH\/NLM) – https:\/\/www.ncbi.nlm.nih.gov\/gene\/ - ZFIN – https:\/\/zfin.org\/ - Ensembl – https:\/\/www.ensembl.org\/ - Nature Methods (2015): A proposal for validation of antibodies – https:\/\/www.nature.com\/articles\/nmeth.3230 --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"Adding 0.2 ml of distilled water will yield a concentration of 500 ug\/ml \/ 100 ug","offer_id":53046717710701,"sku":"FY12166","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_d8b003b1-edd2-4ae8-96da-384088dc67ba.jpg?v=1782236968","url":"https:\/\/www.ebiohippo.com\/products\/tfb2m-antibody-transcription-factor-b2-mitochondrial-bha17135069","provider":"BioHippo","version":"1.0","type":"link"}