{"product_id":"tmem180-antibody-mfsd13a-bha17130013","title":"TMEM180 Antibody \/ MFSD13A","description":"\u003ch2\u003eOverview\u003c\/h2\u003e \u003cp\u003eTMEM180 Antibody \/ MFSD13A is an antibody targeting \u003cstrong\u003eMFSD13A\u003c\/strong\u003e, raised in \u003cstrong\u003eRabbit\u003c\/strong\u003e for protein detection and localization studies where these specifications are required.\u003c\/p\u003e \u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e \u003cul\u003e \u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e MFSD13A.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eAntibody identity:\u003c\/strong\u003e Polyclonal (rabbit origin); Rabbit IgG.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eConjugate\/label:\u003c\/strong\u003e Unconjugated (affects detection chemistry and multiplex compatibility).\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Antigen affinity purified.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eSpecies reactivity:\u003c\/strong\u003e Human.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eListed applications:\u003c\/strong\u003e WB, FACS, ELISA (refer to on-page specifications for application-specific guidance).\u003c\/li\u003e \u003c\/ul\u003e  \u003ch2\u003eBiological background\u003c\/h2\u003e \u003cp\u003eMFSD13A (Major Facilitator Superfamily Domain Containing 13A) is located on human chromosome 10q24.32. The MFSD13A protein is ubiquitously expressed in brain, lung and other tissues. Structurally, the encoded protein is reported to be 27160 Da in mass. The MFSD13A (also known as TMEM180; C10orf77; bA18I14.8) gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, chicken, frog, etc. 234 organisms have orthologs with human gene MFSD13A. The MFSD13A gene might be genetic modifiers of pancreatic cancer tumorigenesis.\u003c\/p\u003e \u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eComparative expression profiling across cell types, tissues, or perturbations (e.g., drug treatment, genetic editing, or differentiation).\u003c\/li\u003e \u003cli\u003eSubcellular localization and trafficking studies, including co-localization with pathway markers in microscopy-based assays.\u003c\/li\u003e \u003cli\u003eIntegration of protein-level measurements with transcriptomics or proteomics to relate abundance to regulation and phenotype.\u003c\/li\u003e \u003c\/ul\u003e \u003ch2\u003eCommon research applications\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eWestern blotting: researchers commonly compare relative signal levels across conditions and use appropriate negative\/positive controls for interpretation.\u003c\/li\u003e \u003cli\u003eFlow cytometry: researchers commonly compare relative signal levels across conditions and use appropriate negative\/positive controls for interpretation.\u003c\/li\u003e \u003cli\u003eELISA: researchers commonly compare relative signal levels across conditions and use appropriate negative\/positive controls for interpretation.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eInterpretation should account for antibody-dependent factors such as epitope accessibility, isoforms, and sample preparation differences across workflows.\u003c\/p\u003e \u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e \u003cul\u003e \u003cli\u003e\n\u003cstrong\u003eIsoforms and PTMs:\u003c\/strong\u003e many targets have multiple isoforms and post-translational modifications that can shift apparent signal or localization; interpret bands\/signals accordingly.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eEpitope context:\u003c\/strong\u003e binding can depend on protein conformation and sample processing; region information in the title\/immunogen can help anticipate what may be detected.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eSpecies differences:\u003c\/strong\u003e predicted or validated reactivity may vary by ortholog sequence and sample context; confirm in your model system.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eControl concepts:\u003c\/strong\u003e include negative controls (no-primary\/isotype), and where possible genetic controls (KO\/KD) or independent antibodies to strengthen conclusions.\u003c\/li\u003e \u003c\/ul\u003e \u003c!-- Sources (internal): - UniProtKB entry Q14CX5 — UniProt — https:\/\/www.uniprot.org\/uniprotkb\/Q14CX5 - Gene search: MFSD13A — NCBI Gene — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=MFSD13A - Ensembl search: MFSD13A — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=MFSD13A - PubMed search: MFSD13A antibody — PubMed — https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=MFSD13A+antibody - Reactome search: MFSD13A — Reactome — https:\/\/reactome.org\/content\/query?q=MFSD13A --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.5mg\/ml if reconstituted with 0.2ml sterile DI water \/ 100 ug","offer_id":53046479618413,"sku":"RQ8456","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_9d93b058-3e79-4e67-9bf1-b5d957b72800.jpg?v=1772000854","url":"https:\/\/www.ebiohippo.com\/products\/tmem180-antibody-mfsd13a-bha17130013","provider":"BioHippo","version":"1.0","type":"link"}