{"product_id":"tnfrsf9-4-1bb-monoclonal-antibody-bha10565048","title":"TNFRSF9\/4-1BB Monoclonal Antibody","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eThis is a monoclonal anti-TNFRSF9\/4-1BB antibody raised in Human, with confirmed utility in ELISA. It is designed to detect TNFRSF9\/4-1BB protein in Human and supports researchers working in immunology contexts.\u003c\/p\u003e\n\n\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Recombinant Human TNFRSF9 protein — determines the epitope region; confirm compatibility with sample preparation and expected post-translational modifications.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHost species (Human):\u003c\/strong\u003e Requires anti-human-IgG secondary reagents for indirect detection.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMonoclonal format:\u003c\/strong\u003e Single-epitope binding provides high specificity and lot-to-lot reproducibility. Confirm epitope accessibility under your assay conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIsotype (IgG2):\u003c\/strong\u003e Matched secondary antibodies and isotype controls required. Compatible with standard Protein A\/G purification workflows.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurification (Affinity chromatography):\u003c\/strong\u003e Enriches for specific immunoglobulin classes; reduces non-specific background vs. crude antisera.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eBiological background\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eTNFRSF9\/4-1BB\u003c\/strong\u003e (also referred to as 4 1BB, 4 1BB ligand receptor, 4-1BB ligand receptor, 4-1BB Ligand Receptor T Cell, 4-1BB, mouse, homolog of, Antigen 4-1BB Homolog, CD 137, CD137, CD137 antigen, CDw137, HLDA VI, Homolog of mouse 4 1BB, ILA, induced by lymphocyte activation (ILA), Induced by lymphocyte activation, Interleukin activated receptor homolog of mouse Ly63, Ly63, mouse, homolog of, MGC2172, OTTHUMP00000044294, Receptor protein 4 1BB, T cell antigen 4 1BB homolog, T cell antigen ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNF receptor superfamily member 9, TNFRSF9, TNR9_HUMAN, Tumor necrosis factor receptor superfamily member 9) is a protein target studied in Human systems. Expression, subcellular localization, and post-translational modifications vary across cell types and disease states — factors critical to antibody-based detection design. Consult UniProt, NCBI Gene, and primary literature for current annotation of TNFRSF9\/4-1BB biology in immunology.\u003c\/p\u003e\n\n\u003ch2\u003eCommon research applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eELISA:\u003c\/strong\u003e Quantification of soluble target in biological fluids or culture supernatants. Ensure samples are within the linear detection range.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIsotype controls:\u003c\/strong\u003e Use an isotype-matched (IgG2 from Human) control at equivalent concentration to assess non-specific background.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCross-reactivity:\u003c\/strong\u003e Confirm the clone does not cross-react with related family members under your assay conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMatrix effects:\u003c\/strong\u003e Sample matrix can affect performance; pilot dilution linearity and spike-recovery experiments are advised for quantitative studies.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecies reactivity:\u003c\/strong\u003e Confirmed for Human. Extrapolation to untested species requires empirical validation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\u003cem\u003eThis product is a recombinant monoclonal antibody expressed in HEK293F cells.\u003c\/em\u003e\u003c\/p\u003e\n\n\u003c!-- Sources:\n- UniProt: https:\/\/www.uniprot.org\n- NCBI Gene: https:\/\/www.ncbi.nlm.nih.gov\/gene\n- Cusabio: https:\/\/www.cusabio.com\n- Human Protein Atlas: https:\/\/www.proteinatlas.org\n- PubMed: https:\/\/pubmed.ncbi.nlm.nih.gov\n--\u003e","brand":"CUSABIO TECHNOLOGY LLC","offers":[{"title":"50 uL","offer_id":53248380273005,"sku":"CSB-RA023984A1HU-50UL","price":210.0,"currency_code":"USD","in_stock":true},{"title":"100 uL","offer_id":53248451346797,"sku":"CSB-RA023984A1HU-100UL","price":350.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/CSB-RA023984A1HU-ELISA-1.jpg?v=1776795261","url":"https:\/\/www.ebiohippo.com\/products\/tnfrsf9-4-1bb-monoclonal-antibody-bha10565048","provider":"BioHippo","version":"1.0","type":"link"}