{"product_id":"u-blot-pan-di-methyllysine-rabbit-mab-bha21821411","title":"U-Blot® Pan-Di-Methyllysine Rabbit mAb","description":"\u003cdiv class=\"bhp-desc\"\u003e\n\u003cstyle\u003e.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}.bhp-desc p{margin:0 0 12px}.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}.bhp-desc .bhp-qc-badge{display:inline-block;background:#e6f4ea;color:#1a7a3c;border:1px solid #a8d5b5;border-radius:4px;padding:6px 14px;font-size:14px;font-weight:600}.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}.bhp-desc .bhp-cat-pill{display:inline-block;background:#003366;color:#fff;border-radius:20px;padding:3px 12px;font-size:13px;margin-bottom:10px}\u003c\/style\u003e\n\u003cspan class=\"bhp-cat-pill\"\u003ePost-Translational Modification Antibody\u003c\/span\u003e\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eU-Blot® Pan-Di-Methyllysine Rabbit mAb is a monoclonal antibody raised in Rabbit that specifically recognizes \u003cstrong\u003eDi-Methyllysine\u003c\/strong\u003e (Lysine di-methylation [ε-amino group (Nε) of the lysine (Lys, K) side chain]). It is designed for detection and analysis of the Lysine di-methylation [ε-amino group (Nε) of the lysine (Lys, K) side chain] post-translational modification across research applications.\u003c\/p\u003e\n\u003cp\u003eDi-Methyllysine (Kme2) is a crucial reversible post-translational modification of proteins, which occurs on the ε-amino group of lysine residues, including symmetric and asymmetric dimethylation forms. It is widely distributed in histones and non-histone proteins, and participates in regulating chromatin remodeling, gene transcription, RNA splicing, DNA damage repair, cell cycle progression and signal transduction. Aberrant lysine dimethylation is closely associated with tumorigenesis, inflammation, neurodegeneration and metabolic disorders, serving as a vital biomarker for epigenetic and pathological research.\u003c\/p\u003e\n\u003ch2\u003eValidated Applications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eApplication\u003c\/th\u003e\n\u003ctd\u003eWestern Blot\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eHost\u003c\/th\u003e\n\u003ctd\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eClonality\u003c\/th\u003e\n\u003ctd\u003eMonoclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eConjugate\u003c\/th\u003e\n\u003ctd\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eMolecular Weight\u003c\/th\u003e\n\u003ctd\u003eCalculated: Multiple | Observed: Multiple\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eReactivity Notes\u003c\/h2\u003e\n\u003cp\u003eThis antibody shows reactivity with multiple species. It targets the Lysine di-methylation [ε-amino group (Nε) of the lysine (Lys, K) side chain] modification and is suitable for Western Blot.\u003c\/p\u003e\n\u003cdiv class=\"bhp-qc-badge\"\u003eValidated for Western Blot\u003c\/div\u003e\n\u003ch2\u003eSafety \u0026amp; Handling\u003c\/h2\u003e\n\u003cdiv class=\"bhp-warning-box\"\u003e\n\u003cstrong\u003eFor Research Use Only (RUO).\u003c\/strong\u003e Not for diagnostic or therapeutic use. Store at -20°C; avoid repeated freeze-thaw cycles.\u003c\/div\u003e\n\u003ch2\u003eRelated Products\u003c\/h2\u003e\n\u003cp\u003eExplore other UcallM Biosciences post-translational modification antibodies available through BioHippo.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"UcallM Biosciences Inc","offers":[{"title":"100 uL","offer_id":53438909677933,"sku":"WT9144-100UL","price":550.0,"currency_code":"USD","in_stock":true},{"title":"300 uL","offer_id":53438909710701,"sku":"WT9144-300UL","price":1400.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Ucallm_WT9144-100.jpg?v=1781281835","url":"https:\/\/www.ebiohippo.com\/products\/u-blot-pan-di-methyllysine-rabbit-mab-bha21821411","provider":"BioHippo","version":"1.0","type":"link"}