{"product_id":"u-blot-pan-succinyllysine-mouse-mab-bha21821416","title":"U-Blot® Pan-Succinyllysine Mouse mAb","description":"\u003cdiv class=\"bhp-desc\"\u003e\n\u003cstyle\u003e.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}.bhp-desc p{margin:0 0 12px}.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}.bhp-desc .bhp-qc-badge{display:inline-block;background:#e6f4ea;color:#1a7a3c;border:1px solid #a8d5b5;border-radius:4px;padding:6px 14px;font-size:14px;font-weight:600}.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}.bhp-desc .bhp-cat-pill{display:inline-block;background:#003366;color:#fff;border-radius:20px;padding:3px 12px;font-size:13px;margin-bottom:10px}\u003c\/style\u003e\n\u003cspan class=\"bhp-cat-pill\"\u003ePost-Translational Modification Antibody\u003c\/span\u003e\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eU-Blot® Pan-Succinyllysine Mouse mAb is a monoclonal antibody raised in Mouse that specifically recognizes \u003cstrong\u003eSuccinyllysine\u003c\/strong\u003e (Lysine succinylation [Lys(K)]). It is designed for detection and analysis of the Lysine succinylation [Lys(K)] post-translational modification across research applications.\u003c\/p\u003e\n\u003cp\u003eSuccinyllysine (abbreviated as Ksucc) is an acylation-type post-translational modification occurring on lysine residues of proteins. By covalently attaching a succinyl group to the side chain of lysine, this modification markedly alters the charge and physicochemical properties of amino acid residues. Ksucc is widely distributed on both histone and non-histone proteins, and is critically involved in chromatin remodeling, gene transcription, energy metabolism, and mitochondrial function. It plays important regulatory roles in various pathological processes including cancer, metabolic diseases, and inflammatory responses, serving as a key target in the crosstalk between metabolism and epigenetics.\u003c\/p\u003e\n\u003ch2\u003eValidated Applications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eApplication\u003c\/th\u003e\n\u003ctd\u003eWestern Blot\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eRecommended Dilution\u003c\/th\u003e\n\u003ctd\u003eWB 1:500-1:1000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eHost\u003c\/th\u003e\n\u003ctd\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eClonality\u003c\/th\u003e\n\u003ctd\u003eMonoclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eIsotype\u003c\/th\u003e\n\u003ctd\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eReactivity\u003c\/th\u003e\n\u003ctd\u003eHuman, Mouse, Rat\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eConjugate\u003c\/th\u003e\n\u003ctd\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003ePurification\u003c\/th\u003e\n\u003ctd\u003eProtein G and immunogen affinity purified\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eMolecular Weight\u003c\/th\u003e\n\u003ctd\u003eCalculated: Multiple | Observed: Multiple\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003ch2\u003eImmunogen \/ Antigen\u003c\/h2\u003e\n\u003cp\u003epolypeptide\u003c\/p\u003e\n\u003ch2\u003eReactivity Notes\u003c\/h2\u003e\n\u003cp\u003eThis antibody shows reactivity with Human, Mouse, Rat. It targets the Lysine succinylation [Lys(K)] modification and is suitable for Western Blot.\u003c\/p\u003e\n\u003cdiv class=\"bhp-qc-badge\"\u003eValidated for Western Blot\u003c\/div\u003e\n\u003ch2\u003eSafety \u0026amp; Handling\u003c\/h2\u003e\n\u003cdiv class=\"bhp-warning-box\"\u003e\n\u003cstrong\u003eFor Research Use Only (RUO).\u003c\/strong\u003e Not for diagnostic or therapeutic use. Store at -20°C. Avoid repeated freeze-thaw cycles | Stable for 12 months from date of receipt \/ reconstitution.\u003c\/div\u003e\n\u003ch2\u003eRelated Products\u003c\/h2\u003e\n\u003cp\u003eExplore other UcallM Biosciences post-translational modification antibodies available through BioHippo.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"UcallM Biosciences Inc","offers":[{"title":"100 uL","offer_id":53438907449709,"sku":"WT9169-100UL","price":750.0,"currency_code":"USD","in_stock":true},{"title":"300 uL","offer_id":53438907482477,"sku":"WT9169-300UL","price":1950.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Ucallm_WT9169-100.jpg?v=1781281838","url":"https:\/\/www.ebiohippo.com\/products\/u-blot-pan-succinyllysine-mouse-mab-bha21821416","provider":"BioHippo","version":"1.0","type":"link"}