{"product_id":"vdac1-antibody-bha11904571","title":"VDAC1 Antibody","description":"\u003cp\u003eVoltage-dependent anion-selective channel protein 1 (VDAC1), also known as mitochondrial porin 1, is a pivotal protein embedded in the outer mitochondrial membrane. It serves as the primary gateway for the exchange of ions and metabolites between mitochondria and the cytosol, playing a critical role in cellular energy metabolism, calcium homeostasis, and apoptosis. VDAC1 also functions as a docking site for key regulatory proteins, including hexokinase and BCL2L1, linking mitochondrial activity to glycolysis and cell survival pathways.\u003c\/p\u003e\n\n\u003cp\u003eIn the context of neurodegenerative diseases, VDAC1 has emerged as a key player in mitochondrial dysfunction—a hallmark of disorders such as Alzheimer’s, Parkinson’s, and Huntington’s disease. Its involvement in the formation of the mitochondrial permeability transition pore complex (PTPC) facilitates the release of pro-apoptotic factors, triggering neuronal cell death. Dysregulation of VDAC1 expression or function has been associated with increased oxidative stress, impaired bioenergetics, and neuroinflammation.\u003c\/p\u003e\n\n\u003cp\u003eGiven its central role in mitochondrial physiology and apoptosis, VDAC1 is increasingly recognized as a promising therapeutic target in neuroscience and neurodegeneration research. Understanding its molecular interactions and regulatory mechanisms may unlock new strategies for mitigating neuronal loss and preserving cognitive function.\u003c\/p\u003e","brand":"StressMarq Biosciences Inc.","offers":[{"title":"100 ug \/ Unconjugated","offer_id":53040790241645,"sku":"SMC-456D","price":337.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ ATTO 390","offer_id":53040846668141,"sku":"SMC-456D-A390","price":392.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ ATTO 488","offer_id":53040846700909,"sku":"SMC-456D-A488","price":391.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ ATTO 594","offer_id":53040846733677,"sku":"SMC-456D-A594","price":391.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ APC","offer_id":53040846766445,"sku":"SMC-456D-APC","price":390.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ BI","offer_id":53040846799213,"sku":"SMC-456D-BI","price":386.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ FITC","offer_id":53040846831981,"sku":"SMC-456D-FITC","price":381.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ HRP","offer_id":53040846864749,"sku":"SMC-456D-HRP","price":377.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ PCP","offer_id":53040846897517,"sku":"SMC-456D-PCP","price":390.0,"currency_code":"USD","in_stock":true},{"title":"100 ug \/ RPE","offer_id":53040846930285,"sku":"SMC-456D-RPE","price":388.0,"currency_code":"USD","in_stock":true},{"title":"12 ug \/ Unconjugated","offer_id":53040846963053,"sku":"SMC-456S","price":45.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/SMC-456_VDAC1_Antibody_N152B-23_ICC-IF_Human_Neuroblastoma-cells-SH-SY5Y-Composite-1.png?v=1771832150","url":"https:\/\/www.ebiohippo.com\/products\/vdac1-antibody-bha11904571","provider":"BioHippo","version":"1.0","type":"link"}