{"product_id":"ybx1-polyclonal-antibody-bha10318120","title":"YBX1 Polyclonal Antibody","description":"\u003cdiv class=\"bhp-desc\"\u003e\n\u003cstyle\u003e\n.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}\n.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}\n.bhp-desc p{margin:0 0 12px}\n.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}\n.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-qc-badge{display:inline-block;background:#e6f4ea;color:#1a7a3c;border:1px solid #a8d5b5;border-radius:4px;padding:6px 14px;font-size:14px;font-weight:600}\n.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}\n\u003c\/style\u003e\n\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eThis protein mediates pre-mRNA alternative splicing regulation. It binds to splice sites in pre-mRNA and regulates splice site selection and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It can regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro).\u003c\/p\u003e\n\n\u003ch2\u003eValidated Applications \u0026amp; Recommended Dilutions\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eApplication\u003c\/th\u003e\n\u003cth\u003eRecommended Dilution\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImmunohistochemistry\u003c\/td\u003e\n\u003ctd\u003eIHC 1:30-1:150\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\n\u003ch2\u003eAntibody Specifications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n\u003ctr\u003e\n\u003cth\u003eTarget\u003c\/th\u003e\n\u003ctd\u003eYBX1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eHost Species\u003c\/th\u003e\n\u003ctd\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eClonality\u003c\/th\u003e\n\u003ctd\u003ePolyclonal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eIsotype\u003c\/th\u003e\n\u003ctd\u003eIgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eConjugate\u003c\/th\u003e\n\u003ctd\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003ePurification\u003c\/th\u003e\n\u003ctd\u003eAntigen Affinity Purification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eConcentration\u003c\/th\u003e\n\u003ctd\u003e0.6 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\n\u003ch2\u003eImmunogen\u003c\/h2\u003e\n\u003cp\u003eSynthetic peptide of human YBX1 UniProt: \u003ca href=\"https:\/\/www.uniprot.org\/uniprot\/P67809\" target=\"_blank\"\u003eP67809\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eSpecies Reactivity \u0026amp; Cross-Reactivity\u003c\/h2\u003e\n\u003cp\u003eValidated for: Human, Mouse, Rat. Verify suitability in your sample type prior to use. For species or applications not listed in the datasheet, consult our technical team before purchase.\u003c\/p\u003e\n\n\u003ch2\u003eStorage \u0026amp; Handling\u003c\/h2\u003e\n\u003cdiv class=\"bhp-warning-box\"\u003e\u003cp\u003eStore at -20℃ Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eStorage Buffer:\u003c\/strong\u003e PBS with 0.05% NaN3 and 40% Glycerol,pH7.4\u003c\/p\u003e\n\n\u003ch2\u003eRelated Products\u003c\/h2\u003e\n\u003cp\u003eBrowse additional antibodies targeting YBX1 and complementary reagents — including secondary antibodies, blocking buffers, and detection kits — available through BioHippo.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Elabscience Biotechnology Co Ltd","offers":[{"title":"20 uL","offer_id":53336496734573,"sku":"E-AB-53542_20μL","price":73.0,"currency_code":"USD","in_stock":true},{"title":"60 uL","offer_id":53336688755053,"sku":"E-AB-53542_60μL","price":143.0,"currency_code":"USD","in_stock":true},{"title":"120 uL","offer_id":53336688787821,"sku":"E-AB-53542_120μL","price":240.0,"currency_code":"USD","in_stock":true},{"title":"200 uL","offer_id":53336688820589,"sku":"E-AB-53542_200μL","price":399.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/vfvHy5.jpg?v=1778921593","url":"https:\/\/www.ebiohippo.com\/products\/ybx1-polyclonal-antibody-bha10318120","provider":"BioHippo","version":"1.0","type":"link"}