{"product_id":"ym-08-bhb11900013","title":"YM-08","description":"\u003cp\u003eYM-08 is a blood-brain barrier-permeable derivative of the Hsp70 inhibitor MKT-077. Although slightly less potent in vitro, YM-08 selectively reduces pathogenic tau in brain slices, a capability not observed with its predecessor. Its improved pharmacokinetics and reduced renal retention suggest lower nephrotoxicity, enhancing its therapeutic potential. YM-08’s ability to target tau pathology in the central nervous system positions it as a promising candidate for treating tauopathies such as Alzheimer’s disease and frontotemporal dementia.\u003c\/p\u003e","brand":"StressMarq Biosciences Inc.","offers":[{"title":"10 mg","offer_id":53040942055789,"sku":"SIH-122-10MG","price":189.0,"currency_code":"USD","in_stock":true},{"title":"25 mg","offer_id":53040966500717,"sku":"SIH-122-25MG","price":378.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/SIH-122_YM-08_Chemical_Structure.png?v=1771837629","url":"https:\/\/www.ebiohippo.com\/products\/ym-08-bhb11900013","provider":"BioHippo","version":"1.0","type":"link"}