{"product_id":"ywhaq-antibody-14-3-3-theta-bha17136334","title":"YWHAQ Antibody \/ 14-3-3 theta","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eYWHAQ Antibody \/ 14-3-3 theta is a anti-YWHAQ Rabbit antibody Recombinant Rabbit Monoclonal clone HHF-25 supplied in Purified format. Recommended for workflows such as Western blot (WB), IHC-P with listed reactivity in Human. Reported localization: Cytoplasm.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e YWHAQ\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntibody details:\u003c\/strong\u003e Rabbit, Recombinant Rabbit Monoclonal, clone HHF-25, isotype Rabbit IgG\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Purified\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplications (as listed):\u003c\/strong\u003e WB, IHC-P\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cdiv\u003eYWHAQ, also known as 14-3-3 theta, is a member of the 14-3-3 protein family that regulates diverse cellular processes including signal transduction, apoptosis, and cell cycle control. It functions as an adaptor protein, binding to phosphorylated partners to influence their localization, stability, and activity. Researchers commonly use a YWHAQ antibody to study these signaling networks.    \u003cp\u003e YWHAQ is widely expressed in human tissues and has been linked to neuronal function, stress responses, and cancer progression. Its interaction with kinases, transcription factors, and cytoskeletal proteins makes it an important regulator of cellular homeostasis. Employing a YWHAQ antibody enables detailed investigation of its role in pathways controlling growth, survival, and differentiation. \u003c\/p\u003e\n\u003cp\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eConnecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).\u003c\/li\u003e\n\u003cli\u003eConsidering isoforms and post-translational regulation when interpreting protein-level changes.\u003c\/li\u003e\n\u003cli\u003eComparing results across species and model systems with matched controls.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWestern blotting:\u003c\/strong\u003e compare relative abundance and activation-state changes across conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunohistochemistry:\u003c\/strong\u003e map target signal in tissue context and compare regions\/phenotypes.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eInterpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.\u003c\/p\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eSignal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.\u003c\/li\u003e\n\u003cli\u003eSpecies differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eAntibody notes:\u003c\/strong\u003e Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.\u003c\/p\u003e\u003c!-- Sources (internal): - UniProt search — UniProt — https:\/\/www.uniprot.org\/uniprotkb?query=YWHAQ - NCBI Gene search — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=YWHAQ - Ensembl search — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=YWHAQ - Human Protein Atlas search — HPA — https:\/\/www.proteinatlas.org\/search\/YWHAQ - PubMed (review) — NLM — https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=YWHAQ+review --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg\/ml BSA \/ 100 ul","offer_id":53047325196653,"sku":"RQ8915","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_40f63381-5991-4a9a-ae71-d42ad70cf02c.jpg?v=1772019446","url":"https:\/\/www.ebiohippo.com\/products\/ywhaq-antibody-14-3-3-theta-bha17136334","provider":"BioHippo","version":"1.0","type":"link"}