{"product_id":"z-guggulsterone-bhb11900369","title":"Z-Guggulsterone","description":"\u003cp\u003eZ-Guggulsterone is a bioactive phytosteroid that functions as a selective antagonist of the farnesoid X receptor (FXR), inhibiting FXR transactivation and modulating bile acid signaling. It also acts as an inhibitor of the retinoic acid receptor (RAR) pathway. In neuroscience, Z-Guggulsterone has shown potential in attenuating astrocyte-mediated neuroinflammation by suppressing the toll-like receptor 4 (TLR4) pathway. This anti-inflammatory activity positions it as a candidate for further investigation in neurodegenerative disease models where glial activation and chronic inflammation are key pathological features.\u003c\/p\u003e","brand":"StressMarq Biosciences Inc.","offers":[{"title":"5 mg","offer_id":53040952869229,"sku":"SIH-591-5MG","price":111.0,"currency_code":"USD","in_stock":true},{"title":"25 mg","offer_id":53040973021549,"sku":"SIH-591-25MG","price":459.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/SIH-591-Z-Guggulsterone-Chemical-Structure.png?v=1771837664","url":"https:\/\/www.ebiohippo.com\/products\/z-guggulsterone-bhb11900369","provider":"BioHippo","version":"1.0","type":"link"}