{"product_id":"zebrafish-dlx2a-antibody-dlx2-bha17136413","title":"Zebrafish Dlx2a Antibody \/ Dlx2","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eZebrafish Dlx2a Antibody \/ Dlx2 is a anti-DLX2A Rabbit antibody Polyclonal (rabbit origin) supplied in Antigen affinity purified format. Recommended for workflows such as Western blot (WB) with listed reactivity in Zebrafish.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e DLX2A\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntibody details:\u003c\/strong\u003e Rabbit, Polyclonal (rabbit origin), isotype Rabbit Ig\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Antigen affinity purified\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplications (as listed):\u003c\/strong\u003e WB\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cdiv\u003eDlx2a, or distal less homeobox two a, is a transcription factor that belongs to the Dlx family of homeodomain proteins. In zebrafish, Dlx2a plays a critical role in the development of the nervous system and craniofacial structures. It is particularly important for the differentiation and migration of neural crest cells, which give rise to a wide range of tissues including cartilage, bone, and peripheral neurons.\u003cp\u003eDuring embryogenesis, Dlx2a is expressed in the developing forebrain, pharyngeal arches, and olfactory placodes. It functions by regulating gene expression programs that control patterning and morphogenesis of the head and facial structures. Dlx2a is also involved in the formation of inhibitory neurons in the forebrain, contributing to the proper development of neural circuits.\u003c\/p\u003e\n\u003cp\u003eZebrafish Dlx2a is widely used as a molecular marker for neural crest cells and for studying the genetic pathways that underlie craniofacial development and neural differentiation. Because of its high conservation with mammalian Dlx genes, it is also valuable for modeling congenital disorders affecting the face and brain, and for investigating the regulatory networks that guide vertebrate head formation.\u003c\/p\u003e\n\u003c\/div\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eConnecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).\u003c\/li\u003e\n\u003cli\u003eConsidering isoforms and post-translational regulation when interpreting protein-level changes.\u003c\/li\u003e\n\u003cli\u003eComparing results across species and model systems with matched controls.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\u003cli\u003e\n\u003cstrong\u003eWestern blotting:\u003c\/strong\u003e compare relative abundance and activation-state changes across conditions.\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003eInterpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.\u003c\/p\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eSignal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.\u003c\/li\u003e\n\u003cli\u003eSpecies differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eAntibody notes:\u003c\/strong\u003e Polyclonal antibodies recognize multiple epitopes, which can broaden the epitope footprint and may increase sensitivity in some contexts.\u003c\/p\u003e\u003c!-- Sources (internal): - UniProt search — UniProt — https:\/\/www.uniprot.org\/uniprotkb?query=DLX2A - NCBI Gene search — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=DLX2A - Ensembl search — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=DLX2A - Human Protein Atlas search — HPA — https:\/\/www.proteinatlas.org\/search\/DLX2A - PubMed (review) — NLM — https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=DLX2A+review --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.5mg\/ml if reconstituted with 0.2ml sterile DI water \/ 100 ug","offer_id":53047328014701,"sku":"RZ1218","price":539.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_80b27103-0a6e-467b-b597-274ea9f9a129.jpg?v=1772019457","url":"https:\/\/www.ebiohippo.com\/products\/zebrafish-dlx2a-antibody-dlx2-bha17136413","provider":"BioHippo","version":"1.0","type":"link"}