{"product_id":"zebrafish-fasn-antibody-fatty-acid-synthase-fas-bha17136418","title":"Zebrafish Fasn Antibody \/ Fatty acid synthase \/ Fas","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eZebrafish Fasn Antibody \/ Fatty acid synthase \/ Fas is a anti-Zebrafish Fasn Rabbit antibody Polyclonal (rabbit origin) supplied in Antigen affinity purified format. Recommended for workflows such as Western blot (WB), IHC-P with listed reactivity in Zebrafish. Reported localization: Cytoplasm.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e Zebrafish Fasn\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntibody details:\u003c\/strong\u003e Rabbit, Polyclonal (rabbit origin), isotype Rabbit Ig\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Antigen affinity purified\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplications (as listed):\u003c\/strong\u003e WB, IHC-P\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cdiv\u003eFatty acid synthase, also called Fas and Fasn, is a large multi enzyme protein complex that catalyzes the synthesis of long chain saturated fatty acids from acetyl coenzyme A and malonyl coenzyme A in the presence of nicotinamide adenine dinucleotide phosphate. In zebrafish, fatty acid synthase is essential for lipid metabolism and plays a central role in energy storage, membrane formation, and signaling pathways during development and growth.\u003cp\u003eFatty acid synthase is highly expressed in metabolically active tissues such as the liver, brain, and developing embryos. It supports rapid cell division and tissue expansion by supplying fatty acids needed for phospholipid and triglyceride production. In zebrafish embryos, the expression of fatty acid synthase begins early and is critical for proper organogenesis and survival.\u003c\/p\u003e\n\u003cp\u003eAltered regulation of fatty acid synthase is associated with metabolic disorders, cancer, and developmental abnormalities. Due to its evolutionary conservation and functional importance, zebrafish fatty acid synthase is widely used as a model to study lipid biosynthesis, energy metabolism, and the effects of dietary and environmental factors on fat production. It is also a valuable target for screening compounds that modulate lipogenesis or impact metabolic health.\u003c\/p\u003e\n\u003c\/div\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eConnecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).\u003c\/li\u003e\n\u003cli\u003eConsidering isoforms and post-translational regulation when interpreting protein-level changes.\u003c\/li\u003e\n\u003cli\u003eComparing results across species and model systems with matched controls.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWestern blotting:\u003c\/strong\u003e compare relative abundance and activation-state changes across conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunohistochemistry:\u003c\/strong\u003e map target signal in tissue context and compare regions\/phenotypes.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eInterpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.\u003c\/p\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eSignal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.\u003c\/li\u003e\n\u003cli\u003eSpecies differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eAntibody notes:\u003c\/strong\u003e Polyclonal antibodies recognize multiple epitopes, which can broaden the epitope footprint and may increase sensitivity in some contexts.\u003c\/p\u003e\u003c!-- Sources (internal): - UniProt search — UniProt — https:\/\/www.uniprot.org\/uniprotkb?query=Zebrafish+Fasn - NCBI Gene search — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=Zebrafish+Fasn - Ensembl search — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=Zebrafish+Fasn - Human Protein Atlas search — HPA — https:\/\/www.proteinatlas.org\/search\/Zebrafish+Fasn - PubMed (review) — NLM — https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Zebrafish+Fasn+review --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.5mg\/ml if reconstituted with 0.2ml sterile DI water \/ 100 ug","offer_id":53047328604525,"sku":"RZ1223","price":539.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_b65f8c35-a110-4d82-b63c-721419cfe743.jpg?v=1772019460","url":"https:\/\/www.ebiohippo.com\/products\/zebrafish-fasn-antibody-fatty-acid-synthase-fas-bha17136418","provider":"BioHippo","version":"1.0","type":"link"}