{"product_id":"zebrafish-mylz2-antibody-fast-skeletal-myosin-light-chain-2-mylpfa-b-bha17136520","title":"Zebrafish Mylz2 Antibody \/ Fast skeletal myosin light chain 2 \/ Mylpfa\/b","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eZebrafish Mylz2 Antibody \/ Fast skeletal myosin light chain 2 \/ Mylpfa\/b is a anti-MYLZ2 Rabbit antibody Polyclonal (rabbit origin) supplied in Antigen affinity purified format. Recommended for workflows such as Western blot (WB), IHC-P with listed reactivity in Zebrafish. Reported localization: Cytoplasm.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e MYLZ2\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntibody details:\u003c\/strong\u003e Rabbit, Polyclonal (rabbit origin), isotype Rabbit Ig\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Antigen affinity purified\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplications (as listed):\u003c\/strong\u003e WB, IHC-P\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cdiv\u003eZebrafish Mylz2 (Fast skeletal myosin light chain 2), also called Mylpfa (Myosin regulatory light chain 2, skeletal muscle isoform A), is a regulatory component of the myosin complex that modulates actin-myosin interactions in fast-twitch skeletal muscle fibers. It is essential for muscle contraction, fiber stability, and efficient locomotor activity during zebrafish development and adulthood.    \u003cp\u003eMylz2 expression is restricted to fast skeletal muscle, making it a valuable marker for studying muscle specialization and performance. The human ortholog of Mylz2 is MYL1, which encodes myosin light chain 1\/3, a protein involved in contractile regulation of human skeletal muscle. This conservation underscores its role in fundamental muscle biology across vertebrates. \u003c\/p\u003e\n\u003cp\u003eUsing a high-quality Zebrafish Mylz2 antibody enables reliable detection in assays such as western blot, immunohistochemistry, and immunofluorescence. A Zebrafish Mylz2 antibody from\u003c\/p\u003e\n\u003c\/div\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eConnecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).\u003c\/li\u003e\n\u003cli\u003eConsidering isoforms and post-translational regulation when interpreting protein-level changes.\u003c\/li\u003e\n\u003cli\u003eComparing results across species and model systems with matched controls.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWestern blotting:\u003c\/strong\u003e compare relative abundance and activation-state changes across conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunohistochemistry:\u003c\/strong\u003e map target signal in tissue context and compare regions\/phenotypes.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eInterpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.\u003c\/p\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eSignal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.\u003c\/li\u003e\n\u003cli\u003eSpecies differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eAntibody notes:\u003c\/strong\u003e Polyclonal antibodies recognize multiple epitopes, which can broaden the epitope footprint and may increase sensitivity in some contexts.\u003c\/p\u003e\u003c!-- Sources (internal): - UniProt search — UniProt — https:\/\/www.uniprot.org\/uniprotkb?query=MYLZ2 - NCBI Gene search — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=MYLZ2 - Ensembl search — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=MYLZ2 - Human Protein Atlas search — HPA — https:\/\/www.proteinatlas.org\/search\/MYLZ2 - PubMed (review) — NLM — https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=MYLZ2+review --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.5mg\/ml in PBS with 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3. \/ 200 ul","offer_id":53047331651949,"sku":"RZ1326","price":539.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_a655073b-1d38-41cb-be5f-78e916766125.jpg?v=1772019478","url":"https:\/\/www.ebiohippo.com\/products\/zebrafish-mylz2-antibody-fast-skeletal-myosin-light-chain-2-mylpfa-b-bha17136520","provider":"BioHippo","version":"1.0","type":"link"}