{"product_id":"zebrafish-sox32-antibody-casanova-bha17136508","title":"Zebrafish Sox32 Antibody \/ Casanova","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eZebrafish Sox32 Antibody \/ Casanova is a anti-SOX32 Rabbit antibody Polyclonal (rabbit origin) supplied in Antigen affinity purified format. Recommended for workflows such as Western blot (WB) with listed reactivity in Zebrafish.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e SOX32\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntibody details:\u003c\/strong\u003e Rabbit, Polyclonal (rabbit origin), isotype Rabbit Ig\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Antigen affinity purified\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplications (as listed):\u003c\/strong\u003e WB\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cdiv\u003eZebrafish Sox32, also known as SRY related HMG box 32, is a transcription factor that plays a key role in endoderm formation and early developmental processes. Sox32 belongs to the Sox family of transcription factors, which are defined by the presence of a high mobility group (HMG) DNA binding domain. In zebrafish embryos, Sox32 is essential for specifying endodermal cell fate and for the proper development of organs derived from endodermal tissues such as the pancreas and liver.\u003cp\u003eZebrafish Sox32 is considered a functional counterpart to members of the human SOX family, although there is no single direct human ortholog due to evolutionary divergence. The conserved role of Sox family proteins in regulating developmental gene expression makes Sox32 a critical target for studying early embryogenesis and cell lineage determination.\u003c\/p\u003e\n\u003cp\u003eThe use of a Zebrafish Sox32 antibody enables researchers to detect and study the expression patterns of Sox32 during early development. Such antibodies are essential tools for applications including western blot, immunohistochemistry, and immunofluorescence to visualize Sox32 in specific tissues or cell types. By applying a Zebrafish Sox32 antibody, scientists can gain deeper insights into the transcriptional networks that control endoderm differentiation and organogenesis.\u003c\/p\u003e\n\u003cp\u003eThere are no known isoforms of zebrafish Sox32, and its expression is tightly regulated during the early stages of development. Reagents such as a Zebrafish Sox32 antibody are also useful in exploring how perturbations in Sox32 function can lead to defects in endoderm specification or other developmental abnormalities.\u003c\/p\u003e\n\u003c\/div\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eConnecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).\u003c\/li\u003e\n\u003cli\u003eConsidering isoforms and post-translational regulation when interpreting protein-level changes.\u003c\/li\u003e\n\u003cli\u003eComparing results across species and model systems with matched controls.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\u003cli\u003e\n\u003cstrong\u003eWestern blotting:\u003c\/strong\u003e compare relative abundance and activation-state changes across conditions.\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003eInterpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.\u003c\/p\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eSignal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.\u003c\/li\u003e\n\u003cli\u003eSpecies differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eAntibody notes:\u003c\/strong\u003e Polyclonal antibodies recognize multiple epitopes, which can broaden the epitope footprint and may increase sensitivity in some contexts.\u003c\/p\u003e\u003c!-- Sources (internal): - UniProt search — UniProt — https:\/\/www.uniprot.org\/uniprotkb?query=SOX32 - NCBI Gene search — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=SOX32 - Ensembl search — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=SOX32 - Human Protein Atlas search — HPA — https:\/\/www.proteinatlas.org\/search\/SOX32 - PubMed (review) — NLM — https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=SOX32+review --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.5mg\/ml if reconstituted with 0.2ml sterile DI water \/ 100 ug","offer_id":53047331815789,"sku":"RZ1313","price":539.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_2d1c8ab2-2da9-425e-b44b-0c7a61846167.jpg?v=1772019475","url":"https:\/\/www.ebiohippo.com\/products\/zebrafish-sox32-antibody-casanova-bha17136508","provider":"BioHippo","version":"1.0","type":"link"}