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Aldh7A1-KO

SKU : BHAM00019

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	TBD
Description	Model Description: Exon 2-5 of Aldh7A1 gene was deleted to generate Aldh7A1 knockout mice. Official Symbol: Aldh7a1 NCBI ID: 110695 MGI ID: 108186 Ensembl ID: ENSMUSG00000053644 Pubmed: Aldh7a1 Human Ortholog: ALDH7A1
Nomenclature	C57BL/6JSmoc-Aldh7A1^em1Smoc
Exon	Exon 2-5
Disease	Pyridoxine-Dependent Epilepsy
Disease	Nervous System Disease
KI/KO Gene	Aldh7a1
Synonyms	Atq1, D18Wsu181e

Reference	Sarah A Oppelt 1, Erin M Sennott 2, Dean R Tolan; Aldolase-B knockout in mice phenocopies hereditary fructose intolerance in humans. Mol Genet Metab. 2015 Mar;114(3):445-50. Al-Shekaili HH, Petkau TL, Pena I, Lengyell TC, Verhoeven-Duif NM, Ciapaite J, Bosma M, van Faassen M, Kema IP, Horvath G, Ross C, Simpson EM, Friedman JM, van Karnebeek C, Leavitt BR, A novel mouse model for pyridoxine-dependent epilepsy due to antiquitin deficiency. Hum Mol Genet. 2020 Nov 25;29(19):3266-3284

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