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Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

353 Result Found
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  • Dmpk-KO

    Dmpk-KO

    Dmpk-KO

    • KI/KO Gene : Dmpk
    • Nomenclature : C57BL/6JSmoc-Dm
    • Exon : Exon 1-7
    • Description : Model Descripti
    • Disease : Myotonic Dystro
  • Dmd-Q995X

    Dmd-Q995X

    Dmd-Q995X

    • KI/KO Gene : Dmd
    • Nomenclature : C57BL/6JSmoc-Dm
    • Description : Model Descripti
    • Disease : Duchenne muscul
    • Synonyms : dys, mdx, pke,
  • Des-KO

    Des-KO

    Des-KO

    • KI/KO Gene : Des
    • Nomenclature : C57BL/6JSmoc-De
    • Exon : Exon 2-5
    • Description : Model Descripti
    • Reference : MGI:5704370
  • Dbt-KO

    Dbt-KO

    Dbt-KO

    • KI/KO Gene : Dbt
    • Nomenclature : C57BL/6JSmoc-Db
    • Exon : Exon 2
    • Description : Model Descripti
    • Disease : Maple Syrup Uri
  • Ext1-Flox

    Ext1-Flox

    Ext1-Flox

    • KI/KO Gene : Ext1
    • Nomenclature : C57BL/6JSmoc-Ex
    • Exon : Exon s
    • Description : Model Descripti
    • Disease : Hereditary Mult
  • Fem1b-KO

    Fem1b-KO

    Fem1b-KO

    • KI/KO Gene : Fem1b
    • Exon : Exon 2
    • Description : Model Descripti
    • Disease : Type 2 Diabetes
    • Synonyms : mKIAA0396
  • F8-KO(2)

    F8-KO(2)

    F8-KO(2)

    • KI/KO Gene : F8
    • Nomenclature : C57BL/6JSmoc-F8
    • Exon : Exon 1-26.
    • Description : Model Descripti
    • Disease : factor VIII def
  • G6pc-Flox

    G6pc-Flox

    G6pc-Flox

    • KI/KO Gene : G6pc
    • Nomenclature : C57BL/6JSmoc-G6
    • Exon : Exon 3
    • Description : Model Descripti
    • Disease : Glycogen Storag
  • Ghr-KO(2)

    Ghr-KO(2)

    Ghr-KO(2)

    • KI/KO Gene : Ghr
    • Nomenclature : C57BL/6JSmoc-Gh
    • Exon : Exon 1-7.
    • Description : Model Descripti
    • Disease : Laron syndrome
  • Gck-Flox

    Gck-Flox

    Gck-Flox

    • KI/KO Gene : Gck
    • Nomenclature : C57BL/6JSmoc-Gc
    • Exon : Exon s
    • Description : Model Descripti
    • Disease : Familial Hyperi
  • Gcdh-KO

    Gcdh-KO

    Gcdh-KO

    • KI/KO Gene : Gcdh
    • Nomenclature : C57BL/6JSmoc-Gc
    • Exon : Exon 3-7
    • Description : Model Descripti
    • Disease : Glutaric Acidem
  • Gbe1-KO

    Gbe1-KO

    Gbe1-KO

    • KI/KO Gene : Gbe1
    • Nomenclature : C57BL/6JSmoc-Gb
    • Exon : Exon 2
    • Description : Model Descripti
    • Disease : Glycogen Storag
  • Gba-Flox

    Gba-Flox

    Gba-Flox

    • KI/KO Gene : Gba
    • Nomenclature : C57BL/6JSmoc-Gb
    • Exon : Exon 8-11
    • Description : Model Descripti
    • Disease : Gaucher's Disea
  • HBV-Tg

    HBV-Tg

    HBV-Tg

    • KI/KO Gene : HBV
    • Nomenclature : B6.Cg-Tg(HBV)Sm
    • Description : Model Descripti
    • Synonyms : Hepatitis B vir
    • Reference : MGI:3699178
  • Hnf4a-Flox

    Hnf4a-Flox

    Hnf4a-Flox

    • KI/KO Gene : Hnf4a
    • Nomenclature : C57BL/6JSmoc-Hn
    • Exon : Exon 2.
    • Description : Model Descripti
    • Disease : Fanconi Syndrom
  • Hif1a-Flox

    Hif1a-Flox

    Hif1a-Flox

    • KI/KO Gene : Hif1a
    • Nomenclature : C57BL/6JSmoc-Hi
    • Exon : Exon 2
    • Description : Model Descripti
    • Disease : Von Hippel-Lind
  • hCD81

    hCD81

    hCD81

    • KI/KO Gene : Cd81
    • Nomenclature : C57BL/6JSmoc-Cd
    • Description : Model Descripti
    • Synonyms : Tapa1, Tapa-1,
    • Application : Hdv Infection R
  • Ikzf3-KO

    Ikzf3-KO

    Ikzf3-KO

    • KI/KO Gene : Ikzf3
    • Nomenclature : C57BL/6JSmoc-Ik
    • Exon : Exon 8
    • Description : Model Descripti
    • Disease : Systemic Lupus
  • Ifnar1-KO

    Ifnar1-KO

    Ifnar1-KO

    • KI/KO Gene : Ifnar1
    • Nomenclature : C57BL/6JSmoc-If
    • Exon : Exon 3-11
    • Description : Model Descripti
    • Synonyms : Ifar IFN-alpha/
  • Krt14-R131C

    Krt14-R131C

    Krt14-R131C

    • KI/KO Gene : Krt14
    • Nomenclature : C57BL/6JSmoc-Kr
    • Description : Model Descripti
    • Disease : epidermolysis b
    • Synonyms : K14, CK-14, Krt
  • KPC

    KPC

    KPC

    • KI/KO Gene : Trp53
    • Nomenclature : C57BL/6JSmoc-Tr
    • Description : Model Descripti
    • Disease : Pancreatic Carc
    • Synonyms : bbl; bfy; bhy;
  • Lmx1a-Flox

    Lmx1a-Flox

    Lmx1a-Flox

    • KI/KO Gene : Lmx1a
    • Nomenclature : C57BL/6JSmoc-Lm
    • Exon : Exon s
    • Description : Model Descripti
    • Disease : Parkinson's Dis
  • Lmna-c.C1827T

    Lmna-c.C1827T

    Lmna-c.C1827T

    • KI/KO Gene : Lmna
    • Nomenclature : C57BL/6JSmoc-Lm
    • Description : Model Descripti
    • Disease : Progeria
    • Synonyms : Dhe
  • Lepr-KO

    Lepr-KO

    Lepr-KO

    • KI/KO Gene : Lepr
    • Nomenclature : C57BL/6JSmoc-Le
    • Exon : Exon 5
    • Description : Model Descripti
    • Disease : Type 2 Diabetes
  • Mc4r-KO

    Mc4r-KO

    Mc4r-KO

    • KI/KO Gene : Mc4r
    • Nomenclature : C57BL/6JSmoc-Mc
    • Exon : Exon 1
    • Description : Model Descripti
    • Disease : obesity
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