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Zmpste24-KO

SKU : BHAM00351

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KO-18011
Description	Model Description: Exon4-6 of Zmpste24 gene were deleted to generate Zmpste24 knockout mice. Click here to download the brochure. Official Symbol: Zmpste24 NCBI ID: 230709 MGI ID: 1890508 Ensembl ID: ENSMUSG00000043207 Pubmed: Zmpste24 Human Ortholog: ZMPSTE24
Exon	Exon 4-6
Application	Premature Aging Disease Hutchinson-Gilford Progeria Syndrome (Hgps)
Disease	Achalasia
Disease	Rare Disease
KI/KO Gene	Zmpste24
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Lmna-KO(NM-K0-210380) mice.
Synonyms	MADB, FACE1, STE24, Face-1, Ste24p, D030046F19, A530043O15Rik

Reference	MGI:5641710 Yang SH, Procaccia S, Jung HJ, Nobumori C, Tatar A, Tu Y, Bayguinov YR, Hwang SJ, Tran D, Ward SM, Fong LG, Young SG, Mice that express farnesylated versions of prelamin A in neurons develop achalasia. Hum Mol Genet. 2015 May 15;24(10):2826-40

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