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Mc4r-KO

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KO-200357
Description	Model Description: Exon 1 of Mc4r gene was deleted to generate Mc4r knockout mice. Official Symbol: Mc4r NCBI ID: 17202 MGI ID: 99457 Ensembl ID: ENSMUSG00000047259 Pubmed: Mc4r Human Ortholog: MC4R
Nomenclature	C57BL/6JSmoc-Mc4r^em1Smoc
Exon	Exon 1
Application	Therapeutic Antibody Target
Disease	obesity
Disease	Cardio-metabolic Disease
KI/KO Gene	Mc4r
Synonyms	Pkcp, Mc4-r

Reference	MGI:3579532 Huszar D, et al., Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell. 1997 Jan 10;88(1):131-41

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