R26-LSL-SmoM2W539L-IRES-tdTomato-BHAM00299

Mfr.No.	NM-KI-200035
Description	Model Description: These mice harbor a SA-loxp-stop-loxp-SmoM2(W539L)-IRES-tdTomato-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. W539L point mutation of the mouse gene (SmoM2), which corresponds to the W535L mutation in the human sequence. Official Symbol: Gt(ROSA)26Sor NCBI ID: 14910 MGI ID: 104735 Ensembl ID: ENSMUSG00000086429 Pubmed: Gt(ROSA)26Sor Human Ortholog: On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Nomenclature	C57BL/6JSmoc-Gt(ROSA)26Sor^{em1(SA-loxp-stop-loxp-SmoM2(W539L)-IRES-tdTomato-WPRE-polyA)Smoc}
Application	Medulloblastoma
KI/KO Gene	Gt(ROSA)26Sor
Synonyms	R26,ROSA26,AV258896,Gtrgeo26,Gtrosa26,Thumpd3as1

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R26-LSL-SmoM2W539L-IRES-tdTomato