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Tyro3-KO

SKU : BHAM00348

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KO-200558
Description	Model Description: Exon 3 of Tyro3 gene was deleted to generate Tyro3 knockout mice. Official Symbol: Tyro3 NCBI ID: 22174 MGI ID: 104294 Ensembl ID: ENSMUSG00000027298 Pubmed: Tyro3 Human Ortholog: TYRO3
Nomenclature	C57BL/6JSmoc-Tyro3^em1Smoc
Exon	Exon 3
Application	Therapeutic Antibody Target
Disease	Autoimmune Disease
Disease	Autoimmune Disease
KI/KO Gene	Tyro3
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Axl-KO(NM-KO-200044) and Mertk-KO(NM-KO-200362) mice.
Synonyms	Brt, Dtk, Rse, Sky, Tif, Etk-2, TK19-2, tk19-1, AI323366, etk2/tyro3

Reference	MGI:3694359 Lu Q, Lemke G, Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family. Science. 2001 Jul 13;293(5528):306-11

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