DNA-Directed RNA Polymerase III Subunit RPC8 (RPC8) Antibody

Mfr.No.	abx014436
Uniprot	B0QYH9, Q5M7Y8, Q96AE3, Q9BY95
Recommended Dilution	Optimal dilutions/concentrations should be determined by the end user.
uniprot enrty name	RPC8_HUMAN
Uniprotkb	Q9Y535 (UniProt, ExPASy)
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Note	This product is for research use only.
Gene Symbol	POLR3H
Tested Application	WB, FCM
String	9606.ENSP00000347345
Buffer	PBS containing 0.09% sodium azide.
Target	RPC8
Purification	Purified through a protein A column, followed by peptide affinity purification.
Description	RPC8 is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. It is acting as nuclear and cytosolic DNA sensor involved in innate immune response. It can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.
Isotype	IgG
Availability	Shipped within 5-10 working days.
Conjugate	Unconjugated
Reactivity	Human, Mouse
Host	Rabbit
Immunogen	KLH-conjugated synthetic peptide between 5-33 amino acids from the N-terminal region of human RPC8.
Clonality	polyclonal

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SKU	Supplier No.	Size	Your price
BHA144111515	abx014436	10 ug	$50.75	Add to Cart
BHA144111515	abx014436	100 ug	$275.50	Add to Cart
BHA144111515	abx014436	200 ug	$362.50	Add to Cart
BHA144111515	abx014436	300 ug	$464	Add to Cart
BHA144111515	abx014436	1 mg	$1297.75	Add to Cart