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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hTLR8/hPD-1
- Nomenclature : C57BL/6JSmoc-Tl
- KI/KO Gene : Pdcd1
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- Description : Model Descripti
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hTNFRSF1B/hFCGR2B
- Nomenclature : C57BL/6JSmoc-Tn
- KI/KO Gene : Fcgr2b
- Research Application : Immunotherapy
- Strain : Developing
- Description : Model Descripti
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hTNFSF15(BALB/c)
- Nomenclature : BALB/cAnSmoc-Tn
- KI/KO Gene : Tnfsf15
- Strain : Developing
- Description : Model Descripti
- Synonyms : Tl1, Tl1a, Vegi
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R26-CAG-LSL-hPLA2R1-IRES-EGFP
- Nomenclature : C57BL/6JSmoc-Gt
- KI/KO Gene : Pla2r1
- Strain : Developing
- Target : Other Targets
- Description : Model Descripti
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Itgam-IRES-hCD89/hMASP2
- Nomenclature : C57BL/6JSmoc-It
- KI/KO Gene : Itgam
- Strain : Developing
- Description : Model Descripti
- Synonyms : CR3, CR3A, MA
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Rag2/IL2rg-KO/hSIRPA(2)/hCD47
- Nomenclature : C57BL/6JSmoc-Si
- KI/KO Gene : IL2RG
- Research Application : Immunotherapy
- Strain : Embryo cryopres
- Target : Immune Checkpoi
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Rag2-KO/hKDR
- Nomenclature : C57BL/6JSmoc-Kd
- KI/KO Gene : Rag2
- Strain : Embryo cryopres
- Description : Model Descripti
- Synonyms : Rag-2
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R26-LSL-hIL5(M-NSG)
- Nomenclature : NOD-PrkdcscidIl
- KI/KO Gene : Gt(ROSA)26Sor
- Strain : Repository Live
- Description : Model Descripti
- Synonyms : R26, ROSA26, AV
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hPCSK9/hANGPTL3(4)
- Nomenclature : C57BL/6JSmoc-Pc
- KI/KO Gene : Pcsk9
- Strain : Developing
- Description : Model Descripti
- Synonyms : AI415265, AI747
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hPD-1/hPVRIG
- Nomenclature : C57BL/6JSmoc-Pd
- KI/KO Gene : Pdcd1
- Strain : Developing
- Description : Model Descripti
- Synonyms : PD-1, Pdc1, Ly1
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hGPRC5D(2)
- Nomenclature : BALB/cAnSmoc-Gp
- KI/KO Gene : Gprc5d
- Strain : Developing
- Description : Model Descripti
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hIL12RB1(2)
- Nomenclature : C57BL/6JSmoc-Il
- KI/KO Gene : Il12rb1
- Strain : Developing
- Description : Model Descripti
- Synonyms : CD212, IL-12R(b
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hIL1RL1/hIL4/hIL4R
- Nomenclature : C57BL/6JSmoc-Il
- KI/KO Gene : IL4Ra
- Strain : Developing
- Description : Model Descripti
- Synonyms : Il4r, CD124
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hIL4/hIL4R/hTSLP
- Nomenclature : C57BL/6JSmoc-Il
- KI/KO Gene : TSLP
- Strain : Developing
- Description : Model Descripti
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hCSF2RB/hIL3/hCSF2
- Nomenclature : C57BL/6JSmoc-Cs
- KI/KO Gene : IL3
- Strain : Developing
- Description : Model Descripti
- Synonyms : BPA, PSF, HCG
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