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Humanized Knockins
Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
698 Result Found
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hTIGIT/hPVR
- KI/KO Gene : TIGIT
- Nomenclature : C57BL/6JSmoc-Ti
- Description : Model Descripti
- Strain : Embryo cryopres
- Synonyms : Vstm3
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hTNFRSF1B(BALB/c)
- KI/KO Gene : Tnfrsf1b
- Nomenclature : BALB/cAnSmoc-Tn
- Description : Model Descripti
- Strain : Developing
- Synonyms : p75, TNFBR, Tnf
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hTNFRSF10C
- KI/KO Gene : Tnfrsf23
- Nomenclature : C57BL/6JSmoc-Tn
- Description : Model Descripti
- Strain : Developing
- Synonyms : SOB, mSOB, Tnfr
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Itgam-IRES-hCD89/hIGHA1
- KI/KO Gene : Itgam
- Nomenclature : C57BL/6JSmoc-It
- Description : Model Descripti
- Strain : Repository Live
- Synonyms : CR3, CR3A, MA
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R26-LSL-hIL2 SP-hIL15(M-NSG)
- KI/KO Gene : Gt(ROSA)26Sor
- Nomenclature : NOD-PrkdcscidIl
- Description : Model Descripti
- Strain : Developing
- Synonyms : R26, ROSA26, AV
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hCD3EDG/hCD20(2)
- KI/KO Gene : CD3E
- Nomenclature : C57BL/6JSmoc-Cd
- Description : Model Descripti
- Strain : Developing
- Synonyms : CD3, T3e, AI5
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hCD3EDG/hCD40/h4-1BB(2)
- KI/KO Gene : CD3E
- Nomenclature : C57BL/6JSmoc-Cd
- Description : Model Descripti
- Strain : Developing
- Synonyms : CD3, T3e, AI5
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hCD40L(BALB/c)
- KI/KO Gene : Cd40lg
- Nomenclature : BALB/cAnSmoc-Cd
- Description : Model Descripti
- Strain : Embryo cryopres
- Synonyms : IGM, IMD3, Ly62
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hCD40/hCD40LG(BALB/c)
- KI/KO Gene : CD40
- Nomenclature : BALB/cAnSmoc-Cd
- Description : Model Descripti
- Strain : Developing
- Synonyms : IGM, p50, Bp5
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hCD47/hSIRPA(2)/hCD38(2)
- KI/KO Gene : SIRPA
- Nomenclature : C57BL/6JSmoc-Si
- Description : Model Descripti
- Strain : Developing
- Synonyms : Bit, P84, SIR
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hCD47(Balb/c,2)
- KI/KO Gene : Cd47
- Nomenclature : BALB/cAnSmoc-Cd
- Description : Model Descripti
- Strain : Embryo cryopres
- Synonyms : IAP, Itgp, AA40
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hCD81/hOCLN
- KI/KO Gene : CD81
- Nomenclature : C57BL/6JSmoc-Cd
- Description : Model Descripti
- Strain : Embryo cryopres
- Synonyms : Tapa1, Tapa-1,