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Humanized Knockins

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

  • hCD7(2)

    hCD7(2)

    • Nomenclature : C57BL/6JSmoc-Cd
    • KI/KO Gene : Cd7
    • Strain : Developing
    • Description : Model Descripti
  • hCD7

    hCD7

    • Nomenclature : C57BL/6JSmoc-Cd
    • KI/KO Gene : Cd7
    • Strain : Repository Live
    • Description : Model Descripti
  • hCD47/hSIRPA(2)/hCD38(2)

    hCD47/hSIRPA(2)/hCD38(2)

    • Nomenclature : C57BL/6JSmoc-Si
    • KI/KO Gene : SIRPA
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Bit, P84, SIR
  • hCEBPA

    hCEBPA

    • Nomenclature : C57BL/6JSmoc-Ce
    • KI/KO Gene : Cebpa
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Cebp, CBF-A, C/
  • hCEACAM6-Tg

    hCEACAM6-Tg

    • Nomenclature : C57BL/6JSmoc-Tg
    • KI/KO Gene : Tgtn(hCEACAM6)1
    • Strain : Developing
    • Target : Tumor Targets
    • Description : Model Descripti
  • hADORA2A(BALB/c)

    hADORA2A(BALB/c)

    • Nomenclature : BALB/cAnSmoc-Ad
    • KI/KO Gene : Adora2a
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : A2AAR,A2aR,AA2A
  • hADAM17

    hADAM17

    • Nomenclature : C57BL/6JSmoc-Ad
    • KI/KO Gene : Adam17
    • Strain : Developing
    • Target : Other Targets
    • Description : Model Descripti
  • hAPOB(1)

    hAPOB(1)

    • Nomenclature : C57BL/6JSmoc-Ap
    • KI/KO Gene : Apob
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Apo B-100,apob-
  • hAPOE3

    hAPOE3

    • Nomenclature : C57BL/6JSmoc-Ap
    • KI/KO Gene : Apoe
    • Research Application : Cardiovascular
    • Strain : Repository Live
    • Target : Metabolic Targe
  • hCALCA

    hCALCA

    • Nomenclature : C57BL/6JSmoc-Ca
    • KI/KO Gene : Calca
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : CA, Ct, Ctn, Ca
  • hIFNG

    hIFNG

    • Nomenclature : C57BL/6JSmoc-If
    • KI/KO Gene : Ifng
    • Strain : Repository Live
    • Description : Model Descripti
    • Synonyms : Ifg, IFN-g
  • hIL2RA/hTNFRSF1B

    hIL2RA/hTNFRSF1B

    • Nomenclature : C57BL/6JSmoc-Il
    • KI/KO Gene : TNFRSF1B
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : p75, TNFBR, T
  • hIL36A/hIL36B/hIL36G

    hIL36A/hIL36B/hIL36G

    • Nomenclature : C57BL/6JSmoc-Il
    • KI/KO Gene : Il1f6
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Fil1, Il1f9, Il
  • hNPM1

    hNPM1

    • Nomenclature : C57BL/6JSmoc-Np
    • KI/KO Gene : Npm1
    • Strain : Repository Live
    • Description : Model Descripti
    • Synonyms : B23, Npm, NO38
  • hPROM1

    hPROM1

    • Nomenclature : C57BL/6JSmoc-Pr
    • KI/KO Gene : Prom1
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Prom, AC133, CD
  • hPOSTN

    hPOSTN

    • Nomenclature : C57BL/6JSmoc-Po
    • KI/KO Gene : Postn
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : PN, PLF, Osf2,
  • hPVRIG(2)

    hPVRIG(2)

    • Nomenclature : C57BL/6JSmoc-Pv
    • KI/KO Gene : Pvrig
    • Strain : Sperm cryoprese
    • Description : Model Descripti
    • Synonyms : Gm36869
  • hROR2

    hROR2

    • Nomenclature : C57BL/6JSmoc-Ro
    • KI/KO Gene : Ror2
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Ntrkr2
  • hREN

    hREN

    • Nomenclature : C57BL/6JSmoc-Re
    • KI/KO Gene : Ren1
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Ren, Rnr, Rn-1,
  • hPVRL2/hPVRIG

    hPVRL2/hPVRIG

    • Nomenclature : C57BL/6JSmoc-Ne
    • KI/KO Gene : Pvrig
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Gm36869
  • hSIGLEC15

    hSIGLEC15

    • Nomenclature : C57BL/6JSmoc-Si
    • KI/KO Gene : Siglec15
    • Research Application : Immunotherapy
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
  • hSIGLEC10

    hSIGLEC10

    • Nomenclature : C57BL/6JSmoc-Si
    • KI/KO Gene : Siglecg
    • Research Application : Immunotherapy
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • hSEMA4D

    hSEMA4D

    • Nomenclature : C57BL/6JSmoc-Se
    • KI/KO Gene : Sema4d
    • Research Application : Immunotherapy
    • Strain : Embryo cryopres
    • Target : Tumor Targets
  • hSIRPA/hCD47(BALB/c)

    hSIRPA/hCD47(BALB/c)

    • Nomenclature : BALB/cAnSmoc-Si
    • KI/KO Gene : SIRPA
    • Research Application : Tumor research
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • hSIRPA(2)/hCD47/hPD-1/hPD-L1

    • Nomenclature : C57BL/6JSmoc-Si
    • KI/KO Gene : Pdcd1
    • Research Application : Immunotherapy
    • Strain : Repository Live
    • Target : Immune Checkpoi