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Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

353 Result Found
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  • Slc6a4-KO

    Slc6a4-KO

    Slc6a4-KO

    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 3-4
    • KI/KO Gene : Slc6a4
    • Description : Model Descripti
    • Synonyms : Htt, Sert, 5-HT
  • Srgap3-KO

    Srgap3-KO

    Srgap3-KO

    • Nomenclature : C57BL/6JSmoc-Sr
    • Exon : Exon 3
    • KI/KO Gene : Srgap3
    • Description : Model Descripti
    • Synonyms : Gbi, WRP, MEGAP
  • Taar1-KO

    Taar1-KO

    Taar1-KO

    • Nomenclature : C57BL/6JSmoc-Ta
    • Exon : Exon 1
    • KI/KO Gene : Taar1
    • Description : Model Descripti
    • Synonyms : Tar1, Trar1, ta
  • Stat3-Flox

    Stat3-Flox

    Stat3-Flox

    • Nomenclature : C57BL/6JSmoc-St
    • Exon : Exon 12-14
    • KI/KO Gene : Stat3
    • Description : Model Descripti
    • Application : Cancer Research
  • Tmprss9-KO

    Tmprss9-KO

    Tmprss9-KO

    • Exon : Exon 3
    • KI/KO Gene : Tmprss9
    • Description : Model Descripti
    • Synonyms : Serase-1B
    • Disease : Autism Spectrum
  • Tmem173-V154M

    Tmem173-V154M

    Tmem173-V154M

    • Nomenclature : C57BL/6JSmoc-Tm
    • KI/KO Gene : Tmem173
    • Description : Model Descripti
    • Application : Sting-Associate
    • Synonyms : ERIS,MPYS,Mita,
  • Uox-KO(2)

    Uox-KO(2)

    Uox-KO(2)

    • Nomenclature : C57BL/6JSmoc-Uo
    • Exon : Exon 3-4.
    • KI/KO Gene : Uox
    • Description : Model Descripti
    • Application : Hyperuricemia R
  • Zmpste24-KO

    Zmpste24-KO

    Zmpste24-KO

    • Exon : Exon 4-6
    • KI/KO Gene : Zmpste24
    • Description : Model Descripti
    • Application : Premature Aging
    • Synonyms : MADB, FACE1, ST
  • hACE2

    hACE2

    hACE2

    • Nomenclature : C57BL/6JSmoc-Ac
    • KI/KO Gene : Ace2
    • Description : Model Descripti
    • Application : Corona Virus Re
    • Synonyms : 2010305L05Rik
  • R26-CAG-LSL-hACE2-IRES-tdTomato

    R26-CAG-LSL-hACE2-IRES-tdTomato

    R26-CAG-LSL-hACE2-IRES-tdTomato

    • Nomenclature : C57BL/6JSmoc-Gt
    • KI/KO Gene : Gt(ROSA)26Sor
    • Description : Model Descripti
    • Application : Corona Virus Re
    • Synonyms : R26,ROSA26,AV25
  • R26-hCD46-IRES-tdTomato

    R26-hCD46-IRES-tdTomato

    R26-hCD46-IRES-tdTomato

    • Nomenclature : C57BL/6JSmoc-Gt
    • KI/KO Gene : Gt(ROSA)26Sor
    • Description : Model Descripti
    • Application : Immune-Related
    • Synonyms : R26,ROSA26,AV25
  • HBV-Tg

    HBV-Tg

    HBV-Tg

    • Nomenclature : B6.Cg-Tg(HBV)Sm
    • KI/KO Gene : HBV
    • Description : Model Descripti
    • Application : Hbv
    • Synonyms : Hepatitis B vir
  • hCD81

    hCD81

    hCD81

    • Nomenclature : C57BL/6JSmoc-Cd
    • KI/KO Gene : Cd81
    • Description : Model Descripti
    • Application : Hdv Infection R
    • Synonyms : Tapa1, Tapa-1,
  • Aire-KO

    Aire-KO

    Aire-KO

    • Nomenclature : C57BL/6JSmoc-Ai
    • Exon : Exon 8
    • KI/KO Gene : Aire
    • Description : Model Descripti
    • Disease : Sjogren's Syndr
  • Ahi1-Flox

    Ahi1-Flox

    Ahi1-Flox

    • Nomenclature : B6;129S-Ahi1tm1
    • Exon : Exon 2
    • KI/KO Gene : Ahi1
    • Description : Model Descripti
    • Application : Joubert Syndrom
  • Apc-L850X

    Apc-L850X

    Apc-L850X

    • Nomenclature : C57BL/6JSmoc-Ap
    • KI/KO Gene : Apc
    • Description : Model Descripti
    • Application : Heterozygotes O
    • Synonyms : CC1, Min, mAPC,
  • Arhgef10-KO

    Arhgef10-KO

    Arhgef10-KO

    • Nomenclature : C57BL/6JSmoc-Ar
    • Exon : Exon 5
    • KI/KO Gene : Arhgef10
    • Description : Model Descripti
    • Synonyms : mKIAA0294, 6430
  • Bsn-KO

    Bsn-KO

    Bsn-KO

    • Nomenclature : C57BL/6JSmoc-Bs
    • Exon : Exon 2
    • KI/KO Gene : Bsn
    • Description : Model Descripti
    • Disease : Epilepsy
  • Brinp1-KO

    Brinp1-KO

    Brinp1-KO

    • Nomenclature : C57BL/6JSmoc-Br
    • Exon : Exon 3
    • KI/KO Gene : Brinp1
    • Description : Model Descripti
    • Synonyms : Dbc1, BRINP, Fa
  • Casp8-Flox

    Casp8-Flox

    Casp8-Flox

    • Nomenclature : C57BL/6JSmoc-Ca
    • Exon : Exon s
    • KI/KO Gene : Casp8
    • Description : Model Descripti
    • Application : Cancer Research
  • Col4a5-R471X

    Col4a5-R471X

    Col4a5-R471X

    • Nomenclature : C57BL/6JSmoc-Co
    • KI/KO Gene : Col4a5
    • Description : Model Descripti
    • Application : Alport Syndrome
    • Disease : X-Linked Alport
  • Cldn16-KO

    Cldn16-KO

    Cldn16-KO

    • Nomenclature : C57BL/6JSmoc-Cl
    • Exon : Exon 2
    • KI/KO Gene : Cldn16
    • Description : Model Descripti
    • Application : Sertoli-Sertoli
  • Cyp19A1-KO

    Cyp19A1-KO

    Cyp19A1-KO

    • Nomenclature : C57BL/6JSmoc-Cy
    • Exon : Exon 2
    • KI/KO Gene : Cyp19a1
    • Description : Model Descripti
    • Synonyms : Ar, ArKO, Int5,
  • Dmpk-KO

    Dmpk-KO

    Dmpk-KO

    • Nomenclature : C57BL/6JSmoc-Dm
    • Exon : Exon 1-7
    • KI/KO Gene : Dmpk
    • Description : Model Descripti
    • Application : Cardiac Conduct
  • Dmd-Q995X

    Dmd-Q995X

    Dmd-Q995X

    • Nomenclature : C57BL/6JSmoc-Dm
    • KI/KO Gene : Dmd
    • Description : Model Descripti
    • Synonyms : dys, mdx, pke,
    • Disease : Duchenne muscul
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