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SNCA (Synuclein Alpha)

Published On 11/12/2019 6:39 PM
SNCA (Synuclein Alpha) 
Gene and Protein Information   (UniProtKB/Swiss-Prot
Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion, and dilation of exocytotic fusion pores (PubMed:28288128, PubMed:30404828). Mechanistically, acts by increasing local Ca (2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis (PubMed:30404828). Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein Receptors) at the presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5 (PubMed:20798282). This chaperone activity is important to sustain normal SNARE-complex assembly during aging (PubMed:20798282). Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity (PubMed:26442590). SYUA_HUMAN,P37840
Alternate names for SNCA Gene
Additional gene information for SNCA Gene

Gene Wiki entry for SNCA Gene
Antibody Products Load More
Anti-Synuclein-Α Antibody Unconjugated BHA10301370
By elabscience
SKU :BHA10301370

SNCA Antibody, FITC Conjugated
By cusabio
SKU :BHA10507691

Anti-Synuclein Alpha (SNCa) Antibody APC BHA10149642
By cloud-clone
SKU :BHA10149642
Anti-SNCA Antibody BHA11302562
By bioworld
SKU :BHA11302562

Anti-SNCA Antibody
By abm
SKU :BHA10931242

SNCA Antibody
By affbiotech
SKU :BHA12900834
Protein Products  LOAD MORE
Alpha Synuclein A30P/A53T Human Recombinant
By prospec
SKU :BHP11004990
Alpha Synuclein Delta-NAC Human Recombinant
By prospec
SKU :BHP11004991

Recombinant Synuclein Alpha (SNCa)
By cloud-clone
SKU :BHP10109412

Alpha Synuclein 96-140 Human Recombinant
By prospec
SKU :BHP11004994
Alpha Synuclein Protein
By stressmarq
SKU :BHP11900127
Assay Products  LOAD MORE
Porcine Alpha-Synuclein,SNCA ELISA Kit
By bioassay
SKU :BHE12110804
SNCa ELISA Kit BHE10805917
By fine-test
SKU :BHE10805917
Human Alpha-Synuclein,SNCA ELISA Kit
By bioassay
SKU :BHE12102957
ELISA Kit For Pig Alpha-Synuclein
By eiaab
SKU :BHE13810912

ELISA Kit For Rat Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1
By eiaab
SKU :BHE13811092
Synuclein Alpha ELISA Kit BHE10103624
By cloud-clone
SKU :BHE10103624
Human Synuclein, Alpha (Non A4 Component Of Amyloid Precursor) Oligomer (SNCA Oligomer) ELISA Kit
By cusabio
SKU :BHE10504485
SNCA ELISA Kit BHE10800251
By fine-test
SKU :BHE10800251

Mouse Alpha-Synuclein,SNCA ELISA Kit
By bioassay
SKU :BHE12109265
Bovine Alpha-Synuclein,SNCA ELISA Kit
By bioassay
SKU :BHE12100391

Rat Alpha-Synuclein(SNCA) ELISA Kit
By cusabio
SKU :BHE10507567
Synuclein Alpha ELISA Kit BHE10103622
By cloud-clone
SKU :BHE10103622
This entry was posted in Gene Database

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